2WUH
 
 | | Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide | | Descriptor: | COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2 | | Authors: | Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E. | | Deposit date: | 2009-10-05 | | Release date: | 2009-12-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
Structure, 17, 2009
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2C5D
 | | Structure of a minimal Gas6-Axl complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | | Deposit date: | 2005-10-26 | | Release date: | 2005-12-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
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1W8A
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2JD4
 | | Mouse laminin alpha1 chain, domains LG4-5 | | Descriptor: | CHLORIDE ION, LAMININ SUBUNIT ALPHA-1, MAGNESIUM ION | | Authors: | Harrison, D, Hussain, S.A, Combs, A.C, Ervasti, J.M, Yurchenco, P.D, Hohenester, E. | | Deposit date: | 2007-01-04 | | Release date: | 2007-02-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure and Cell Surface Anchorage Sites of Laminin {Alpha}1Lg4-5.
J.Biol.Chem., 282, 2007
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1DKA
 | | DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES | | Descriptor: | 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, POTASSIUM ION, ... | | Authors: | Toney, M.D, Hohenester, E, Jansonius, J.N. | | Deposit date: | 1993-06-18 | | Release date: | 1994-10-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites.
Science, 261, 1993
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6FOA
 | | Human Xylosyltransferase 1 apo structure | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Briggs, D.C, Hohenester, E. | | Deposit date: | 2018-02-06 | | Release date: | 2018-05-02 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.869 Å) | | Cite: | Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1.
Structure, 26, 2018
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5AO6
 | | Endo180 D1-4, trigonal form | | Descriptor: | C-TYPE MANNOSE RECEPTOR 2 | | Authors: | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | | Deposit date: | 2015-09-09 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.36 Å) | | Cite: | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
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5AO5
 | | Endo180 D1-4, monoclinic form | | Descriptor: | C-TYPE MANNOSE RECEPTOR 2, SODIUM ION, SULFATE ION | | Authors: | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | | Deposit date: | 2015-09-09 | | Release date: | 2015-10-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Structure, 23, 2015
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2Y38
 | | LAMININ ALPHA5 CHAIN N-TERMINAL FRAGMENT | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LAMININ SUBUNIT ALPHA-5, ... | | Authors: | Hussain, S.A, Carafoli, F, Hohenester, E. | | Deposit date: | 2010-12-19 | | Release date: | 2011-02-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Determinants of Laminin Polymerisation Revealed by the Crystal Structure of the Alpha5 Chain Amino-Terminal Region
Embo Rep., 12, 2011
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1GL4
 | | Nidogen-1 G2/Perlecan IG3 Complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, NIDOGEN-1, ... | | Authors: | Kvansakul, M, Hopf, M, Ries, A, Timpl, R, Hohenester, E. | | Deposit date: | 2001-08-23 | | Release date: | 2001-11-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan
Embo J., 20, 2001
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1B8G
 | | 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE | | Descriptor: | PROTEIN (1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Capitani, G, Hohenester, E, Feng, L, Storici, P, Kirsch, J.F, Jansonius, J.N. | | Deposit date: | 1999-01-31 | | Release date: | 2000-01-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.
J.Mol.Biol., 294, 1999
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1GR3
 | | Structure of the human collagen X NC1 trimer | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ... | | Authors: | Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E. | | Deposit date: | 2001-12-12 | | Release date: | 2002-02-14 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer.
Structure, 10, 2002
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2DKB
 | | DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES | | Descriptor: | 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Toney, M.D, Hohenester, E, Jansonius, J.N. | | Deposit date: | 1994-07-12 | | Release date: | 1994-10-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites.
Science, 261, 1993
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5LF2
 | | Crystal structure of laminin beta2 LE5-LF-LE6 | | Descriptor: | CALCIUM ION, CHLORIDE ION, Laminin subunit beta-2 | | Authors: | Pulido, D, Hohenester, E. | | Deposit date: | 2016-06-30 | | Release date: | 2016-07-27 | | Last modified: | 2017-03-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains.
Matrix Biol., 57-58, 2017
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5MX1
 | | Crystal structure of human chondroadherin | | Descriptor: | CHLORIDE ION, Chondroadherin, NICKEL (II) ION, ... | | Authors: | Paracuellos, P, Hohenester, E. | | Deposit date: | 2017-01-20 | | Release date: | 2017-03-01 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
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5MC9
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5MX0
 | | Crystal structure of human fibromodulin | | Descriptor: | CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ... | | Authors: | Paracuellos, P, Hohenester, E. | | Deposit date: | 2017-01-20 | | Release date: | 2017-03-01 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Matrix Biol., 63, 2017
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5IK7
 | | Laminin A2LG45 I-form, Apo. | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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5IK4
 | | Laminin A2LG45 C-form, Apo. | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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5IK5
 | | Laminin A2LG45 C-form, G6/7 bound. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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5IK8
 | | Laminin A2LG45 I-form, G6/7 bound. | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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1O91
 | | Crystal Structure of a Collagen VIII NC1 Domain Trimer | | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, COLLAGEN ALPHA 1(VIII) CHAIN, SULFATE ION | | Authors: | Kvansakul, M, Bogin, O, Hohenester, E, Yayon, A. | | Deposit date: | 2002-12-10 | | Release date: | 2003-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Collagen Alpha1(Viii) Nc1 Trimer.
Matrix Biol., 22, 2003
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1H4U
 | | Domain G2 of mouse nidogen-1 | | Descriptor: | NIDOGEN-1 | | Authors: | Hopf, M, Gohring, W, Ries, A, Timpl, R, Hohenester, E. | | Deposit date: | 2001-05-14 | | Release date: | 2001-06-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1
Nat.Struct.Biol., 8, 2001
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1H30
 | | C-terminal LG domain pair of human Gas6 | | Descriptor: | CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION | | Authors: | Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E. | | Deposit date: | 2002-08-21 | | Release date: | 2003-01-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
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1BNL
 | | ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN | | Descriptor: | COLLAGEN XVIII, ZINC ION | | Authors: | Ding, Y.-H, Javaherian, K, Lo, K.-M, Chopra, R, Boehm, T, Lanciotti, J, Harris, B.A, Li, Y, Shapiro, R, Hohenester, E, Timpl, R, Folkman, J, Wiley, D.C. | | Deposit date: | 1998-07-30 | | Release date: | 1998-10-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Zinc-dependent dimers observed in crystals of human endostatin.
Proc.Natl.Acad.Sci.USA, 95, 1998
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