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6O83
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BU of 6o83 by Molmil
S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ...
Authors:Hann, Z.S, Lima, C.D.
Deposit date:2019-03-08
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OP8
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BU of 6op8 by Molmil
S. pombe Ubc7/U7BR complex
Descriptor: 1,2-ETHANEDIOL, CUE domain-containing protein 4, mitochondrial, ...
Authors:Hann, Z.S, Lima, C.D.
Deposit date:2019-04-24
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7.
Acta Crystallogr.,Sect.F, 75, 2019
4JSA
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BU of 4jsa by Molmil
Benzenesulfonamide complexed with hCAII H94D
Descriptor: Carbonic anhydrase 2, MERCURIBENZOIC ACID, SULFATE ION, ...
Authors:Martin, D.P, Hann, Z.S, Cohen, S.M.
Deposit date:2013-03-22
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSW
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BU of 4jsw by Molmil
Human carbonic anhydrase II H94C
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Martin, D.P, Hann, Z.S, Cohen, S.M.
Deposit date:2013-03-22
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSS
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BU of 4jss by Molmil
Human carbonic anhydrase II H94D bound to a bidentate inhibitor
Descriptor: 1-hydroxy-2-sulfanylpyridinium, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
Authors:Martin, D.P, Hann, Z.S, Cohen, S.M.
Deposit date:2013-03-22
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSZ
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BU of 4jsz by Molmil
Benzenesulfonamide bound to hCAII H94C
Descriptor: Carbonic anhydrase 2, ZINC ION, benzenesulfonamide
Authors:Martin, D.P, Hann, Z.S, Cohen, S.M.
Deposit date:2013-03-22
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JS6
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BU of 4js6 by Molmil
Crystal structure of inhibitor-free hCAII H94D
Descriptor: Carbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION
Authors:Martin, D.P, Hann, Z.S, Cohen, S.M.
Deposit date:2013-03-22
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
6O82
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BU of 6o82 by Molmil
S. pombe ubiquitin E1 complex with a ubiquitin-AMP mimic
Descriptor: 1,2-ETHANEDIOL, 5'-deoxy-5'-(sulfamoylamino)adenosine, MAGNESIUM ION, ...
Authors:Olsen, S.K, Lima, C.D.
Deposit date:2019-03-08
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Structural basis for adenylation and thioester bond formation in the ubiquitin E1.
Proc.Natl.Acad.Sci.USA, 116, 2019
9B58
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BU of 9b58 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 4
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B59
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BU of 9b59 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 5
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5N
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BU of 9b5n by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5W
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BU of 9b5w by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 5 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5B
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BU of 9b5b by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 7
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5J
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BU of 9b5j by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 5 map and model (Ub(A)-AMP)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5O
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BU of 9b5o by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5Q
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BU of 9b5q by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 2 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5S
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BU of 9b5s by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - cluster 4 map and model (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5D
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BU of 9b5d by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5H
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BU of 9b5h by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 3 map and model (Ub(A)-AMP/PPi/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5X
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BU of 9b5x by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5U
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BU of 9b5u by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B57
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BU of 9b57 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 3
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5K
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BU of 9b5k by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (Ub(A)/ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B55
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BU of 9b55 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 1
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published
9B5F
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BU of 9b5f by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 1 map and model (Ub(A)/ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway
To be published

 

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