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225D
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BU of 225d by Molmil
A TETRAMERIC DNA STRUCTURE WITH PROTONATED CYTOSINE:CYTOSINE BASE PAIRS
Descriptor: DNA (5'-D(*TP*CP*CP*CP*CP*C)-3')
Authors:Gehring, K, Leroy, J.L, Gueron, M.
Deposit date:1995-07-12
Release date:1995-10-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A tetrameric DNA structure with protonated cytosine.cytosine base pairs.
Nature, 363, 1993
8CT8
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BU of 8ct8 by Molmil
Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex
Descriptor: IODIDE ION, PRL-1 phosphatase, Unextended protein
Authors:Fakih, R, Goldstein, R.H, Kozlov, G, Gehring, K.
Deposit date:2022-05-13
Release date:2023-03-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver.
J.Biol.Chem., 299, 2023
1ME0
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BU of 1me0 by Molmil
Chimeric hairpin with 2',5'-linked RNA loop and DNA stem
Descriptor: DNA/RNA (5'-D(*GP*GP*AP*C)-R(P*(U25)P*(U25)P*(C25)P*(5GP))-D(P*GP*TP*CP*C)-3')
Authors:Denisov, A.Y, Hannoush, R.N, Gehring, K, Damha, M.J.
Deposit date:2002-08-07
Release date:2003-08-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A Novel RNA Motif Based on the Structure of Unusually Stable 2',5'-Linked r(UUCG) Loops
J.AM.CHEM.SOC., 125, 2003
8F6D
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BU of 8f6d by Molmil
Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15
Descriptor: ADP-ribosylation factor-like protein 15, Metal transporter CNNM2
Authors:Kozlov, G, Mahbub, L, Gehring, K.
Deposit date:2022-11-16
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15.
Elife, 12, 2023
2QHO
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BU of 2qho by Molmil
Crystal structure of the UBA domain from EDD ubiquitin ligase in complex with ubiquitin
Descriptor: E3 ubiquitin-protein ligase EDD1, Ubiquitin
Authors:Kozlov, G, Gehring, K.
Deposit date:2007-07-02
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD.
J.Biol.Chem., 282, 2007
8SMO
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BU of 8smo by Molmil
Crystal structure of the complex between truncated MLLE domain of PABPC1 and engineered superPAM2 peptide
Descriptor: Polyadenylate-binding protein 1, SULFATE ION, superPAM2
Authors:Kozlov, G, Gehring, K.
Deposit date:2023-04-26
Release date:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the complex between truncated MLLE domain of PABPC1 and engineered superPAM2 peptide
To Be Published
6DJX
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BU of 6djx by Molmil
Crystal Structure of pParkin-pUb-UbcH7 complex
Descriptor: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
Deposit date:2018-05-27
Release date:2018-07-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.801 Å)
Cite:Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
6DFD
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BU of 6dfd by Molmil
Crystal structure of CNNM3 cyclic nucleotide-binding homology domain
Descriptor: Metal transporter CNNM3
Authors:Kozlov, G, Gehring, K.
Deposit date:2018-05-14
Release date:2018-10-31
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.
J. Biol. Chem., 293, 2018
7SOW
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BU of 7sow by Molmil
LaM domain of human LARP1 in complex with UUUUUU
Descriptor: 1,2-ETHANEDIOL, Isoform 2 of La-related protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis of 3'-end RNA recognition by LARP1
To Be Published
7US1
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BU of 7us1 by Molmil
Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, ...
Authors:Fakih, R, Sauve, V, Gehring, K.
Deposit date:2022-04-22
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Structure of the second phosphoubiquitin-binding site in parkin.
J.Biol.Chem., 298, 2022
4F26
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BU of 4f26 by Molmil
Crystal structure of the second RRM domain of human PABPC1 a pH 9.0
Descriptor: Polyadenylate-binding protein 1
Authors:Kozlov, G, Safaee, N, Gehring, K.
Deposit date:2012-05-07
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F25
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BU of 4f25 by Molmil
Crystal structure of the second RRM domain of human PABPC1 at pH 6.0
Descriptor: Polyadenylate-binding protein 1
Authors:Kozlov, G, Safaee, N, Gehring, K.
Deposit date:2012-05-07
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
6PIK
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BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
7SOQ
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BU of 7soq by Molmil
LaM domain of human LARP1 in complex with AAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOV
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BU of 7sov by Molmil
LaM domain of human LARP1 in complex with AAAAAAAAAAA RNA polynucleotide
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOP
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BU of 7sop by Molmil
LaM domain of human LARP1 in complex with AAAUAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*UP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOS
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BU of 7sos by Molmil
LaM domain of human LARP1 in complex with AAAA RNA
Descriptor: Isoform 2 of La-related protein 1, POTASSIUM ION, RNA (5'-R(*AP*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOR
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BU of 7sor by Molmil
LaM domain of human LARP1 in complex with AAA RNA
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOU
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BU of 7sou by Molmil
LaM domain of human LARP1 in complex with AAAAAA polynucleotide
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOO
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BU of 7soo by Molmil
LaM domain of human LARP1
Descriptor: Isoform 2 of La-related protein 1, SODIUM ION, SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
7SOT
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BU of 7sot by Molmil
LaM domain of human LARP1 in complex with AAAAAA oligonucleotide
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2021-11-01
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
6PIH
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BU of 6pih by Molmil
Hexameric ArnA cryo-EM structure
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
5TDA
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BU of 5tda by Molmil
Crystal structure of the UBR-box domain from UBR2 in complex with RLWS N-degron
Descriptor: ARG-LEU-TRP-SER peptide, E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
8GK6
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BU of 8gk6 by Molmil
Crystal structure of extracellular domain of CNNM4 from Echinococcus granulosus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Metal transporter CNNM4, ...
Authors:Shahsavan, A, Gehring, K.
Deposit date:2023-03-17
Release date:2023-12-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimerization of the CNNM extracellular domain.
Protein Sci., 33, 2024
5BU1
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BU of 5bu1 by Molmil
Structure of the truncated C-terminal domain of lpg1496 from Legionella pneumophila
Descriptor: LPG1496, MALONATE ION
Authors:Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2015-06-03
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015

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