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3K0S
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BU of 3k0s by Molmil
Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT mismatched DNA
Descriptor: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP*GP*AP*C*AP*CP*T*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Reumer, G.A, Winterwerp, H.H.K, Sixma, T.K.
Deposit date:2009-09-25
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.
J.Biol.Chem., 285, 2010
1WBB
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BU of 1wbb by Molmil
Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38A mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
1WB9
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BU of 1wb9 by Molmil
Crystal Structure of E. coli DNA Mismatch Repair enzyme MutS, E38T mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
4PGC
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BU of 4pgc by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGN(3,5-diiodotyrosine)PAL
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
Deposit date:2014-05-01
Release date:2015-01-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PG9
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BU of 4pg9 by Molmil
MHC Class I in complex with Sendai virus nucleoprotein peptide FAPGNYPAL
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
Deposit date:2014-05-01
Release date:2015-01-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PGE
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BU of 4pge by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAW
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
Deposit date:2014-05-01
Release date:2015-01-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PGD
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BU of 4pgd by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAF
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
Deposit date:2014-05-01
Release date:2015-01-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PGB
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BU of 4pgb by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNWPAL
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
Authors:Celie, P.H.N, Joosten, R.P, Perrakis, A, Neefjes, J.
Deposit date:2014-05-01
Release date:2015-01-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
2WVR
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BU of 2wvr by Molmil
Human Cdt1:Geminin complex
Descriptor: DNA REPLICATION FACTOR CDT1, GEMININ
Authors:De Marco, V, Perrakis, A.
Deposit date:2009-10-19
Release date:2009-10-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing.
Proc.Natl.Acad.Sci.USA, 106, 2009
8AG6
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BU of 8ag6 by Molmil
human MutSalpha (MSH2/MSH6) binding to DNA with a GT mismatch
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (50-MER), DNA mismatch repair protein Msh2, ...
Authors:Bruekner, S.R, Sixma, T.K.
Deposit date:2022-07-19
Release date:2023-01-25
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Unexpected moves: a conformational change in MutS alpha enables high-affinity DNA mismatch binding.
Nucleic Acids Res., 51, 2023
2XBB
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BU of 2xbb by Molmil
Nedd4 HECT:Ub complex
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE NEDD4, GLYCEROL, UBIQUITIN
Authors:Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S.
Deposit date:2010-04-08
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
2XBF
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BU of 2xbf by Molmil
Nedd4 HECT structure
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE NEDD4
Authors:Maspero, E, Cecatiello, V, Musacchio, A, Polo, S, Pasqualato, S.
Deposit date:2010-04-09
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Structure of the Hect:Ubiquitin Complex and its Role in Ubiquitin Chain Elongation
Embo Rep., 12, 2011
6QML
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BU of 6qml by Molmil
UCHL3 in complex with synthetic, K27-linked diubiquitin
Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
Authors:Murachelli, A.G, Sixma, T.K.
Deposit date:2019-02-07
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
Cell Chem Biol, 28, 2021
1WBD
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BU of 1wbd by Molmil
Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38Q mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
7AI7
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BU of 7ai7 by Molmil
MutS in Intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*TP*TP*AP*GP*CP*TP*TP*AP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*TP*AP*AP*CP*TP*AP*AP*G)-3'), ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AI6
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BU of 7ai6 by Molmil
MutS in mismatch bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein MutS
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AIC
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BU of 7aic by Molmil
MutS-MutL in clamp state (kinked clamp domain)
Descriptor: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AIB
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BU of 7aib by Molmil
MutS-MutL in clamp state
Descriptor: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AI5
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BU of 7ai5 by Molmil
MutS in Scanning state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*AP*AP*TP*TP*CP*GP*CP*CP*CP*TP*AP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*TP*AP*GP*GP*GP*CP*GP*AP*AP*TP*TP*GP*GP*GP*TP*AP*CP*CP*G)-3'), ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
2Y6E
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BU of 2y6e by Molmil
Structure of the D1D2 domain of USP4, the conserved catalytic domain
Descriptor: SULFATE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4, ZINC ION
Authors:Luna-Vargas, M.P.A, Faesen, A.C, van Dijk, W.J, Rape, M, Fish, A, Sixma, T.K.
Deposit date:2011-01-20
Release date:2011-04-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Dusp-Ubl Domain of Usp4 Enhances its Catalytic Efficiency by Promoting Ubiquitin Exchange.
Nat.Commun., 5, 2014
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