2WVR
Human Cdt1:Geminin complex
Summary for 2WVR
Entry DOI | 10.2210/pdb2wvr/pdb |
Related | 1T6F 1UII |
Descriptor | GEMININ, DNA REPLICATION FACTOR CDT1 (2 entities in total) |
Functional Keywords | replication, dna replication license, dna replication inhibitor, phosphoprotein, ubl conjugation, dna replication, dna-binding, polymorphism, proto-oncogene, nucleus, cell cycle, acetylation, coiled coil |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: Q9H211 |
Total number of polymer chains | 3 |
Total formula weight | 107733.75 |
Authors | De Marco, V.,Perrakis, A. (deposition date: 2009-10-19, release date: 2009-10-27, Last modification date: 2024-05-08) |
Primary citation | De Marco, V.,Gillespie, P.J.,Li, A.,Karantzelis, N.,Christodoulou, E.,Klompmaker, R.,Van Gerwen, S.,Fish, A.,Petoukhov, M.V.,Iliou, M.S.,Lygerou, Z.,Medema, R.H.,Blow, J.J.,Svergun, D.I.,Taraviras, S.,Perrakis, A. Quaternary Structure of the Human Cdt1-Geminin Complex Regulates DNA Replication Licensing. Proc.Natl.Acad.Sci.USA, 106:19807-, 2009 Cited by PubMed: 19906994DOI: 10.1073/PNAS.0905281106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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