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7W7H
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BU of 7w7h by Molmil
S Suis FakA-FakB2 complex structure
Descriptor: OLEIC ACID, Predicted kinase related to dihydroxyacetone kinase, SULFATE ION, ...
Authors:Shi, Y, Zang, N, Lou, N, Xu, Y, Sun, J, Huang, M, Zhang, H, Lu, H, Zhou, C, Feng, Y.
Deposit date:2021-12-04
Release date:2022-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging.
Sci Adv, 8, 2022
7CG1
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BU of 7cg1 by Molmil
Solution structure of the sensor domain of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens
Descriptor: Anti-sigma factor RsgI, N-terminal
Authors:Dong, S, Feng, Y.
Deposit date:2020-06-30
Release date:2021-06-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of the sensor domain of the anti-sigma factor RsgI4 in Pseudobacteroides cellulosolvens
To Be Published
7DM4
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BU of 7dm4 by Molmil
Solution structure of ARID4B Tudor domain
Descriptor: AT-rich interactive domain-containing protein 4B
Authors:Ren, J, Yao, H, Hu, W, Perrett, S, Feng, Y, Gong, W.
Deposit date:2020-12-02
Release date:2021-03-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the DNA-binding activity of human ARID4B Tudor domain.
J.Biol.Chem., 296, 2021
7EIN
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BU of 7ein by Molmil
SARS-CoV-2 main proteinase complex with microbial metabolite leupeptin
Descriptor: 3C-like proteinase, leupeptin
Authors:Fu, L.F, Feng, Y, Qi, J.X, Gao, G.F.
Deposit date:2021-03-31
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs.
Mbio, 12, 2021
7ELE
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BU of 7ele by Molmil
Cryo-EM structure of Arabidopsis DCL1 in complex with pre-miRNA 166f
Descriptor: Endoribonuclease Dicer homolog 1, pre-miRNA 166f
Authors:Wei, X, Ke, H, Feng, Y.
Deposit date:2021-04-09
Release date:2021-08-11
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis of microRNA processing by Dicer-like 1.
Nat.Plants, 7, 2021
7ELD
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BU of 7eld by Molmil
Cryo-EM structure of Arabidopsis DCL1 in complex with pri-miRNA 166f
Descriptor: Endoribonuclease Dicer homolog 1, pri-miRNA 166f
Authors:Wei, X, Ke, H, Feng, Y.
Deposit date:2021-04-09
Release date:2021-08-11
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of microRNA processing by Dicer-like 1.
Nat.Plants, 7, 2021
7WDH
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BU of 7wdh by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine, phenol and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2021-12-21
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Engineering Cytochrome P450BM3 Enzymes for Direct Nitration of Unsaturated Hydrocarbons.
Angew.Chem.Int.Ed.Engl., 62, 2023
7WDG
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BU of 7wdg by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, phenol and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2021-12-21
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Engineering Cytochrome P450BM3 Enzymes for Direct Nitration of Unsaturated Hydrocarbons.
Angew.Chem.Int.Ed.Engl., 62, 2023
7Y0S
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BU of 7y0s by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine
Descriptor: Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-TYR-TYR, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-06-06
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine
To Be Published
7Y0R
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BU of 7y0r by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-06-06
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine
To Be Published
7Y0Q
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BU of 7y0q by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with p-toluidine
Descriptor: 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-06-06
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with p-toluidine
To Be Published
7Y0P
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BU of 7y0p by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-06-06
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine
To Be Published
7YJD
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BU of 7yjd by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine
Descriptor: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-07-19
Release date:2023-07-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine
To Be Published
7Y0U
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BU of 7y0u by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine
Descriptor: Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-PHE-PHE, ...
Authors:Jiang, Y, Dong, S, Feng, Y, Cong, Z.
Deposit date:2022-06-06
Release date:2023-06-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine
To Be Published
7XYA
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BU of 7xya by Molmil
The cryo-EM structure of an AlpA-loading complex
Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Wen, A, Feng, Y.
Deposit date:2022-06-01
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of AlpA-dependent transcription antitermination.
Nucleic Acids Res., 50, 2022
7XYB
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BU of 7xyb by Molmil
The cryo-EM structure of an AlpA-loaded complex
Descriptor: AlpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Wen, A, Feng, Y.
Deposit date:2022-06-01
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of AlpA-dependent transcription antitermination.
Nucleic Acids Res., 50, 2022
7YWA
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BU of 7ywa by Molmil
Structure of DinI in complex with RecA filament
Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), DNA damage-inducible protein I, MAGNESIUM ION, ...
Authors:Gao, B, Feng, Y.
Deposit date:2022-08-22
Release date:2022-12-21
Last modified:2023-01-18
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural basis for regulation of SOS response in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XM0
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BU of 7xm0 by Molmil
Crystal structure of Sau3AI-C and DNA substrate complex
Descriptor: DNA (5'-D(*CP*AP*TP*GP*AP*TP*CP*AP*TP*G)-3'), MAGNESIUM ION, Type II restriction enzyme Sau3AI
Authors:Yahui, L, Feng, Y, Jianhua, H.
Deposit date:2022-04-23
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Self-Activation Mechanism of Type IIE Restriction Endonuclease Sau3AI
To Be Published
7MWH
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BU of 7mwh by Molmil
Crystal structure of BAZ2A with DNA
Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ...
Authors:Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2021-05-17
Release date:2022-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of the BAZ2B TAM domain.
Heliyon, 8, 2022
7KSI
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BU of 7ksi by Molmil
Thiophenyl-Pyrazolourea Derivatives as Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
Descriptor: 4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-5-methyl-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2020-11-23
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.726 Å)
Cite:Thiophene-Pyrazolourea Derivatives as Potent, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7KSJ
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BU of 7ksj by Molmil
Thiophenyl-Pyrazolourea Derivatives as Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
Descriptor: 4-(4-{[(2-chloro-6-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2020-11-23
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Thiophene-Pyrazolourea Derivatives as Potent, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7KSK
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BU of 7ksk by Molmil
Thiophenyl-Pyrazolourea Derivatives as Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
Descriptor: 4-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2020-11-23
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Thiophene-Pyrazolourea Derivatives as Potent, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
6JJS
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BU of 6jjs by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition2
Descriptor: ACETATE ION, PhnH
Authors:Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
Deposit date:2019-02-26
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
6JJT
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BU of 6jjt by Molmil
Crystal structure of an enzyme from Penicillium herquei in condition1
Descriptor: CITRIC ACID, DI(HYDROXYETHYL)ETHER, PhnH
Authors:Fen, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
Deposit date:2019-02-26
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure and proposed mechanism of an enantioselective hydroalkoxylation enzyme from Penicillium herquei.
Biochem.Biophys.Res.Commun., 516, 2019
7S1N
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BU of 7s1n by Molmil
N-Aromatic-Substituted Indazole Derivatives as Brain Penetrant and Orally Bioavailable JNK3 Inhibitors
Descriptor: 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2021-09-02
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:N -Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors.
Acs Med.Chem.Lett., 12, 2021

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