6W6X
| Crystal Structure of ABLE Apo-protein | Descriptor: | ACETATE ION, De novo designed ABLE protein, SULFATE ION | Authors: | Polizzi, N.F. | Deposit date: | 2020-03-18 | Release date: | 2020-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.297 Å) | Cite: | A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
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6W70
| Crystal Structure of apixaban-bound ABLE | Descriptor: | 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE, ACETATE ION, De novo designed ABLE, ... | Authors: | Polizzi, N.F. | Deposit date: | 2020-03-18 | Release date: | 2020-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.296 Å) | Cite: | A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
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6X8N
| Crystal Structure of H49A ABLE mutant | Descriptor: | De novo designed ABLE protein | Authors: | Polizzi, N.F. | Deposit date: | 2020-06-01 | Release date: | 2020-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
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6YB2
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6YB0
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6YAZ
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3BKD
| High resolution Crystal structure of Transmembrane domain of M2 protein | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Transmembrane Domain of Matrix protein M2, ... | Authors: | Stouffer, A.L, Acharya, R, Salom, D. | Deposit date: | 2007-12-06 | Release date: | 2008-01-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for the function and inhibition of an influenza virus proton channel Nature, 451, 2008
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3C9J
| The Crystal structure of Transmembrane domain of M2 protein and Amantadine complex | Descriptor: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, Proton Channel protein M2, transmembrane segment | Authors: | Stouffer, A.L, Acharya, R, Salom, D. | Deposit date: | 2008-02-15 | Release date: | 2008-03-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for the function and inhibition of an influenza virus proton channel Nature, 451, 2008
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3UUG
| Crystal structure of the periplasmic sugar binding protein ChvE | Descriptor: | Multiple sugar-binding periplasmic receptor ChvE, beta-D-glucopyranuronic acid | Authors: | Hu, X, Zhao, J, Binns, A, Degrado, W. | Deposit date: | 2011-11-28 | Release date: | 2012-11-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals. Proc.Natl.Acad.Sci.USA, 110, 2013
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3URM
| Crystal structure of the periplasmic sugar binding protein ChvE | Descriptor: | Multiple sugar-binding periplasmic receptor ChvE, beta-D-galactopyranose | Authors: | Hu, X, Zhao, J, Binns, A, Degrado, W. | Deposit date: | 2011-11-22 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals. Proc.Natl.Acad.Sci.USA, 110, 2013
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3V86
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1MFT
| Crystal Structure Of Four-Helix Bundle Model | Descriptor: | Four-helix bundle model, ZINC ION | Authors: | Lahr, S.J, Stayrook, S.E, North, B, Kaplan, J, Geremia, S, DeGrado, W. | Deposit date: | 2002-08-13 | Release date: | 2004-01-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analysis and Design of Turns in alpha-Helical Hairpins J.Mol.Biol., 346, 2005
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2KV9
| Integrin beta3 subunit in a disulfide linked alphaIIb-beta3 cytosolic domain | Descriptor: | Integrin beta-3 | Authors: | Metcalf, D.G, Kielec, J.M, Valentine, K.G, Wand, A, Bennett, J.S, William, D.F, Moore, D.T, Molnar, K. | Deposit date: | 2010-03-10 | Release date: | 2011-01-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR analysis of the {alpha}IIb{beta}3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc.Natl.Acad.Sci.USA, 107, 2010
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6C4Y
| Cross-alpha Amyloid-like Structure alphaAmG | Descriptor: | Cross-alpha Amyloid-like Structure alphaAmG | Authors: | Liu, L, Zhang, S.Q. | Deposit date: | 2018-01-13 | Release date: | 2018-08-15 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
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6C4X
| Cross-alpha Amyloid-like Structure alphaAmmem | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ZINC ION, cross-alpha amyloid-like membrane peptide alpha-AmMEM | Authors: | Liu, L, Zhang, S.Q. | Deposit date: | 2018-01-13 | Release date: | 2018-08-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
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6C50
| Cross-alpha Amyloid-like Structure alphaAmS | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cross-alpha Amyloid-like Structure alphaAmS, FORMIC ACID | Authors: | Liu, L, Zhang, S.Q. | Deposit date: | 2018-01-13 | Release date: | 2018-08-15 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
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6C4Z
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6C52
| Cross-alpha Amyloid-like Structure alphaTet | Descriptor: | Cross-alpha Amyloid-like Structure alphaTet, GLYCEROL | Authors: | Liu, L, Zhang, S.Q. | Deposit date: | 2018-01-13 | Release date: | 2018-08-15 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
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6C51
| Cross-alpha Amyloid-like Structure alphaAmL | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cross-alpha Amyloid-like Structure alphaAmL, PHOSPHATE ION | Authors: | Liu, L, Zhang, S.Q. | Deposit date: | 2018-01-13 | Release date: | 2018-08-15 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
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4QK7
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5TGY
| NMR structure of holo-PS1 | Descriptor: | PS1, [5,10,15,20-tetrakis(trifluoromethyl)porphyrinato(2-)-kappa~4~N~21~,N~22~,N~23~,N~24~]zinc | Authors: | Polizzi, N.F, Wu, Y. | Deposit date: | 2016-09-28 | Release date: | 2017-08-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | De novo design of a hyperstable non-natural protein-ligand complex with sub- angstrom accuracy. Nat Chem, 9, 2017
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5TGW
| NMR structure of apo-PS1 | Descriptor: | PS1 | Authors: | Polizzi, N.F, Wu, Y. | Deposit date: | 2016-09-28 | Release date: | 2017-08-09 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | De novo design of a hyperstable non-natural protein-ligand complex with sub- angstrom accuracy. Nat Chem, 9, 2017
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