2KV9
Integrin beta3 subunit in a disulfide linked alphaIIb-beta3 cytosolic domain
Summary for 2KV9
| Entry DOI | 10.2210/pdb2kv9/pdb |
| Related | 1KUP 1KUZ 1M8O 2K9J |
| NMR Information | BMRB: 16771 |
| Descriptor | Integrin beta-3 (1 entity in total) |
| Functional Keywords | integrin beta3, beta3, platelet glycoprotein iiia, gpiiia, cd61, cell adhesion |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 8717.81 |
| Authors | Metcalf, D.G.,Kielec, J.M.,Valentine, K.G.,Wand, A.,Bennett, J.S.,William, D.F.,Moore, D.T.,Molnar, K. (deposition date: 2010-03-10, release date: 2011-01-12, Last modification date: 2023-06-14) |
| Primary citation | Metcalf, D.G.,Moore, D.T.,Wu, Y.,Kielec, J.M.,Molnar, K.,Valentine, K.G.,Wand, A.J.,Bennett, J.S.,Degrado, W.F. NMR analysis of the {alpha}IIb{beta}3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc.Natl.Acad.Sci.USA, 107:22481-22486, 2010 Cited by PubMed: 21156831DOI: 10.1073/pnas.1015545107 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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