8JDR
| Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | Descriptor: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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2AQ3
| Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 | Descriptor: | Enterotoxin type C-3, T-cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-17 | Release date: | 2006-03-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APB
| Crystal Structure of the S54N variant of murine T cell receptor Vbeta 8.2 domain | Descriptor: | MALONIC ACID, T-cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APX
| Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | Descriptor: | MALONIC ACID, T cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2AQ2
| Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant | Descriptor: | Enterotoxin type C-3, SODIUM ION, SULFATE ION, ... | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-17 | Release date: | 2006-03-21 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APW
| Crystal Structure of the G17E/A52V/S54N/K66E/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | Descriptor: | MALONIC ACID, T cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APV
| Crystal Structure of the G17E/A52V/S54N/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | Descriptor: | MALONIC ACID, T cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2AQ1
| Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant | Descriptor: | Enterotoxin type C-3, T-cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-17 | Release date: | 2006-03-21 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APF
| Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain | Descriptor: | MALONIC ACID, T cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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2APT
| Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | Descriptor: | MALONIC ACID, T-cell receptor beta chain V | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | Deposit date: | 2005-08-16 | Release date: | 2006-03-21 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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8PKP
| Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | Deposit date: | 2023-06-27 | Release date: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1 To Be Published
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8S4G
| Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D. | Deposit date: | 2024-02-21 | Release date: | 2024-03-13 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex To Be Published
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1SYK
| Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation | Descriptor: | cAMP-dependent protein kinase, alpha-catalytic subunit | Authors: | Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. | Deposit date: | 2004-04-01 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the E230Q mutant of cAMP-dependent
protein kinase reveals an unexpected apoenzyme conformation and an
extended N-terminal A helix. Protein Sci., 14, 2005
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5LCW
| Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution | Descriptor: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | Authors: | Alfieri, C, Chang, L, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | Deposit date: | 2016-06-22 | Release date: | 2016-08-10 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular basis of APC/C regulation by the spindle assembly checkpoint. Nature, 536, 2016
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2LGX
| NMR structure for Kindle-2 N-terminus | Descriptor: | Fermitin family homolog 2 | Authors: | Perera, H.D, Ma, Y, Yang, J, Hirbawi, J, Plow, E.F, Qin, J. | Deposit date: | 2011-08-03 | Release date: | 2011-11-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation. Structure, 19, 2011
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6BA6
| Solution structure of Rap1b/talin complex | Descriptor: | Ras-related protein Rap-1b, Talin-1 | Authors: | Zhu, L, Yang, J, Qin, J. | Deposit date: | 2017-10-12 | Release date: | 2017-12-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation. Nat Commun, 8, 2017
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3MWH
| The 1.4 Ang crystal structure of the ArsD arsenic metallochaperone provides insights into its interactions with the ArsA ATPase | Descriptor: | Arsenical resistance operon trans-acting repressor arsD, GLYCEROL | Authors: | Ye, J, Ajees, A.A, Yang, J, Rosen, B.P. | Deposit date: | 2010-05-05 | Release date: | 2010-05-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The 1.4 A crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPase. Biochemistry, 49, 2010
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6JE9
| Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | Descriptor: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-04 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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6J0B
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath-tube complex in extended state | Descriptor: | Pvc1, Pvc2 | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-23 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0C
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath complex in contracted state | Descriptor: | Pvc2 | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-23 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0F
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath/tube terminator in extended state | Descriptor: | Pvc1, Pvc16 | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-24 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6JE4
| Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | Descriptor: | 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ... | Authors: | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | Deposit date: | 2019-02-04 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.069 Å) | Cite: | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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6J0N
| Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry | Descriptor: | Pvc1, Pvc11, Pvc12, ... | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-25 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0M
| Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry) | Descriptor: | Pvc8 | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-24 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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3HFH
| Crystal structure of tandem FF domains | Descriptor: | Transcription elongation regulator 1 | Authors: | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | Deposit date: | 2009-05-11 | Release date: | 2009-08-18 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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