8BRD
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8BRI
| VaPomAB MSP1D1 nanodisc | Descriptor: | Chemotaxis protein PomA, Flagellar motor protein | Authors: | Hu, H, Taylor, N.M.I. | Deposit date: | 2022-11-23 | Release date: | 2023-06-14 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit. Nat Commun, 14, 2023
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6GL4
| Structure of GluA2o ligand-binding domain (S1S2J) in complex with glutamate and sodium bromide at 1.95 A resolution | Descriptor: | ACETATE ION, BROMIDE ION, GLUTAMIC ACID, ... | Authors: | Venskutonyte, R, Frydenvang, K, Kastrup, J.S. | Deposit date: | 2018-05-22 | Release date: | 2019-05-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors. Neuron, 102, 2019
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6GIV
| Structure of GluA2-N775S ligand-binding domain (S1S2J) in complex with glutamate and Rubidium Bromide at 1.75 A resolution | Descriptor: | BROMIDE ION, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Venskutonyte, R, Frydenvang, K, Kastrup, J.S. | Deposit date: | 2018-05-15 | Release date: | 2019-05-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors. Neuron, 102, 2019
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6LCY
| Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | Authors: | Zhang, Y, Zhang, X, Rao, F, Wang, C. | Deposit date: | 2019-11-20 | Release date: | 2021-03-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis. Nat Metab, 3, 2021
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7LIO
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7LIQ
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7LIP
| X-ray structure of SPOP MATH domain (D140G) | Descriptor: | SULFATE ION, Speckle-type POZ protein | Authors: | Botuyan, M.V, Cui, G, Mer, G. | Deposit date: | 2021-01-27 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication. Sci Adv, 7, 2021
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7LIN
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1C6X
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1C6Y
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1C6Z
| ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP. | Descriptor: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, PROTEIN (PROTEASE) | Authors: | Munshi, S. | Deposit date: | 1999-12-28 | Release date: | 2000-12-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease. Acta Crystallogr.,Sect.D, 56, 2000
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1C70
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8UUZ
| Campylobacter jejuni CosR apo form | Descriptor: | DNA-binding response regulator | Authors: | Zhang, Z. | Deposit date: | 2023-11-02 | Release date: | 2024-01-31 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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8UVK
| CosR DNA bound form II | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*T)-3'), ... | Authors: | Zhang, Z. | Deposit date: | 2023-11-03 | Release date: | 2024-01-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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8UVX
| CosR DNA bound form I | Descriptor: | DNA (5'-D(*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*TP*TP*TP*GP*GP*TP*TP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*T)-3'), DNA-binding response regulator | Authors: | Zhang, Z. | Deposit date: | 2023-11-05 | Release date: | 2024-01-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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6VBA
| Structure of human Uracil DNA Glycosylase (UDG) bound to Aurintricarboxylic acid (ATA) | Descriptor: | 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene]bis(6-hydroxybenzoic acid), Uracil-DNA glycosylase | Authors: | Moiani, D, Arvai, A.S, Tainer, J.A. | Deposit date: | 2019-12-18 | Release date: | 2021-03-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Prog.Biophys.Mol.Biol., 163, 2021
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1SVA
| SIMIAN VIRUS 40 | Descriptor: | SIMIAN VIRUS 40 | Authors: | Stehle, T, Gamblin, S.J, Harrison, S.C. | Deposit date: | 1995-11-27 | Release date: | 1996-06-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structure of simian virus 40 refined at 3.1 A resolution. Structure, 4, 1996
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6XFP
| Crystal Structure of BRAF kinase domain bound to Belvarafenib | Descriptor: | 4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno[3,2-d]pyrimidine-7-carboxamide, CHLORIDE ION, Serine/threonine-protein kinase B-raf | Authors: | Yin, J, Sudhamsu, J. | Deposit date: | 2020-06-16 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma. Nature, 594, 2021
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1SID
| MURINE POLYOMAVIRUS COMPLEXED WITH 3'SIALYL LACTOSE | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, POLYOMAVIRUS COAT PROTEIN VP1 | Authors: | Stehle, T, Harrison, S.C. | Deposit date: | 1995-12-12 | Release date: | 1996-06-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments. Structure, 4, 1996
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3WOH
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7A4V
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7A4U
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4GGV
| Crystal Structure of HmtT Involved in Himastatin Biosynthesis | Descriptor: | Cytochrome P450 superfamily protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhang, H, Chen, J, Wang, H, Zhang, H. | Deposit date: | 2012-08-07 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.331 Å) | Cite: | Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis Febs Lett., 587, 2013
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7T9V
| Crystal structure of hSTING with the agonist, SHR171032 | Descriptor: | (3S,4S)-4-(3-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazol-1-yl}propyl)-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine-8-carboxamide, CALCIUM ION, Stimulator of interferon genes protein | Authors: | Chowdhury, R, Miller, M. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis. Sci Rep, 12, 2022
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