2J83
| Ulilysin metalloprotease in complex with batimastat. | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, GLYCEROL, ... | Authors: | Garcia-Castellanos, R, Tallant, C, Marrero, A, Sola, M, Baumann, U, Gomis-Ruth, F.X. | Deposit date: | 2006-10-18 | Release date: | 2006-12-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substrate Specificity of a Metalloprotease of the Pappalysin Family Revealed by an Inhibitor and a Product Complex. Arch.Biochem.Biophys., 457, 2007
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2JB9
| PhoB response regulator receiver domain constitutively-active double mutant D10A and D53E. | Descriptor: | PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | Authors: | Ferrer-Orta, C, Arribas-Bosacoma, R, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | Deposit date: | 2006-12-05 | Release date: | 2007-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the E. Coli Phob Receiver Domain Give Insights Into Activation J.Mol.Biol., 366, 2007
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2JBA
| PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION | Authors: | Arribas-Bosacoma, R, Ferrer-Orta, C, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | Deposit date: | 2006-12-05 | Release date: | 2007-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation. J.Mol.Biol., 366, 2007
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1OSB
| Conjugative Relaxase TrwC in complex with OriT Dna. Metal-free structure. | Descriptor: | Dna oligonucleotide, SULFATE ION, TrwC protein | Authors: | Guasch, A, Lucas, M, Moncalian, G, Cabezas, M, Perez-Luque, R, Gomis-Ruth, F.X, de la Cruz, F, Coll, M. | Deposit date: | 2003-03-19 | Release date: | 2003-11-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC. Nat.Struct.Biol., 10, 2003
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1AZW
| PROLINE IMINOPEPTIDASE FROM XANTHOMONAS CAMPESTRIS PV. CITRI | Descriptor: | PROLINE IMINOPEPTIDASE | Authors: | Medrano, F.J, Alonso, J, Garcia, J.L, Romero, A, Bode, W, Gomis-Ruth, F.X. | Deposit date: | 1997-11-22 | Release date: | 1999-01-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family. EMBO J., 17, 1998
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3LUM
| Structure of ulilysin mutant M290L | Descriptor: | ARGININE, CALCIUM ION, GLYCEROL, ... | Authors: | Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X. | Deposit date: | 2010-02-18 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | On the relevance of the Met-turn methionine in metzincins. J.Biol.Chem., 285, 2010
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3LQ0
| Zymogen structure of crayfish astacin metallopeptidase | Descriptor: | GLYCEROL, ProAstacin, SULFATE ION, ... | Authors: | Guevara, T, Yiallouros, I, Kappelhoff, R, Bissdorf, S, Stocker, W, Gomis-Ruth, F.X. | Deposit date: | 2010-02-08 | Release date: | 2010-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Proenzyme structure and activation of astacin metallopeptidase J.Biol.Chem., 285, 2010
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3LUN
| Structure of ulilysin mutant M290C | Descriptor: | ARGININE, CALCIUM ION, GLYCEROL, ... | Authors: | Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X. | Deposit date: | 2010-02-18 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | On the relevance of the Met-turn methionine in metzincins. J.Biol.Chem., 285, 2010
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3P24
| Structure of profragilysin-3 from Bacteroides fragilis | Descriptor: | AZIDE ION, BFT-3, GLYCEROL, ... | Authors: | Goulas, T, Arolas, J.L, Gomis-Ruth, F.X. | Deposit date: | 2010-10-01 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog. Proc.Natl.Acad.Sci.USA, 108, 2011
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4IN9
| Structure of karilysin MMP-like catalytic domain in complex with inhibitory tetrapeptide SWFP | Descriptor: | GLYCEROL, Karilysin protease, POTASSIUM ION, ... | Authors: | Guevara, T, Ksiazek, M, Skottrup, P.D, Cerda-Costa, N, Trillo-Muyo, S, de Diego, I, Riise, E, Potempa, J, Gomis-Ruth, F.X. | Deposit date: | 2013-01-04 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of the catalytic domain of the Tannerella forsythia matrix metallopeptidase karilysin in complex with a tetrapeptidic inhibitor. Acta Crystallogr.,Sect.F, 69, 2013
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4QHI
| Crystal structure of Methanocaldococcus jannaschii selecase mutant R36W | Descriptor: | CHLORIDE ION, GLYCEROL, Uncharacterized protein MJ1213, ... | Authors: | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | Deposit date: | 2014-05-28 | Release date: | 2014-07-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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4QHJ
| Crystal structure of Methanocaldococcus jannaschii selecase mutant I100F+H107F | Descriptor: | ACETATE ION, GLYCEROL, Uncharacterized protein MJ1213, ... | Authors: | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | Deposit date: | 2014-05-28 | Release date: | 2014-07-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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4RBM
| Porphyromonas gingivalis gingipain K (Kgp) catalytic and immunoglobulin superfamily-like domains | Descriptor: | (3S)-3,7-diaminoheptan-2-one, ACETATE ION, AZIDE ION, ... | Authors: | de Diego, I, Veillard, F, Sztukowska, M.N, Guevara, T, Potempa, B, Pomowski, A, Huntington, J.A, Potempa, J, Gomis-Ruth, F.X. | Deposit date: | 2014-09-12 | Release date: | 2014-10-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and Mechanism of Cysteine Peptidase Gingipain K (Kgp), a Major Virulence Factor of Porphyromonas gingivalis in Periodontitis. J.Biol.Chem., 289, 2014
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4QHF
| Crystal structure of Methanocaldococcus jannaschii monomeric selecase | Descriptor: | GLYCEROL, NICKEL (II) ION, Uncharacterized protein MJ1213 | Authors: | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | Deposit date: | 2014-05-28 | Release date: | 2014-07-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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4R3V
| Structure of karilysin propeptide and catalytic MMP domain | Descriptor: | CALCIUM ION, GLYCEROL, Karilysin, ... | Authors: | Lopez-Pelegrin, M, Ksiazek, M, Karim, A.Y, Guevara, T, Arolas, J.L, Potempa, J, Gomis-Ruth, F.X. | Deposit date: | 2014-08-18 | Release date: | 2015-01-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | A novel mechanism of latency in matrix metalloproteinases. J.Biol.Chem., 290, 2015
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4QHG
| Crystal structure of Methanocaldococcus jannaschii dimeric selecase | Descriptor: | GLYCEROL, Uncharacterized protein MJ1213, ZINC ION | Authors: | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | Deposit date: | 2014-05-28 | Release date: | 2014-07-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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4QHH
| Crystal structure of Methanocaldococcus jannaschii tetrameric selecase | Descriptor: | GLYCEROL, SODIUM ION, Uncharacterized protein MJ1213, ... | Authors: | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | Deposit date: | 2014-05-28 | Release date: | 2014-07-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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1H5W
| 2.1A Bacteriophage Phi-29 Connector | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, UPPER COLLAR PROTEIN | Authors: | Guasch, A, Pous, J, Ibarra, B, Gomis-Ruth, F.X, Valpuesta, J.M, Sousa, N, Carrascosa, J.L, Coll, M. | Deposit date: | 2001-05-28 | Release date: | 2002-02-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Detailed Architecture of a DNA Translocating Machine: The High-Resolution Structure of the Bacteriophage Phi29 Connector Particle. J.Mol.Biol., 315, 2002
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1GXP
| PhoB effector domain in complex with pho box DNA. | Descriptor: | 5'-D(*CP*CP*CP*GP*TP*GP*AP*CP*AP*AP* CP*TP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*T)-3', 5'-D(*GP*AP*GP*CP*TP*GP*TP*CP*AP*TP* AP*AP*AP*GP*TP*TP*GP*TP*CP*AP*CP*GP*G)-3', PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN | Authors: | Blanco, A.G, Sola, M, Gomis-Ruth, F.X, Coll, M. | Deposit date: | 2002-04-08 | Release date: | 2002-04-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Tandem DNA Recognition by Two-Component Signal Transduction Transcriptional Activator Phob Structure, 10, 2002
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1GXQ
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1OKR
| Three-dimensional structure of S.aureus methicillin-resistance regulating transcriptional repressor MecI. | Descriptor: | CHLORIDE ION, GLYCEROL, METHICILLIN RESISTANCE REGULATORY PROTEIN MECI | Authors: | Garcia-Castellanos, R, Marrero, A, Mallorqui-Fernandez, G, Potempa, J, Coll, M, Gomis-Ruth, F.X. | Deposit date: | 2003-07-28 | Release date: | 2003-10-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-Dimensional Structure of Meci: Molecular Basis for Transcriptional Regulation of Staphylococcal Methicillin Resistance J.Biol.Chem., 278, 2003
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2IWB
| MecR1 unbound extracellular antibiotic-sensor domain. | Descriptor: | GLYCEROL, METHICILLIN RESISTANCE MECR1 PROTEIN, NICKEL (II) ION, ... | Authors: | Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. | Deposit date: | 2006-06-27 | Release date: | 2006-07-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance. J.Mol.Biol., 361, 2006
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1B00
| PHOB RECEIVER DOMAIN FROM ESCHERICHIA COLI | Descriptor: | PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | Authors: | Sola, M, Gomis-Ruth, F.X, Serrano, L, Gonzalez, A, Coll, M. | Deposit date: | 1998-11-15 | Release date: | 1999-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Three-dimensional crystal structure of the transcription factor PhoB receiver domain. J.Mol.Biol., 285, 1999
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2IWA
| Unbound glutaminyl cyclotransferase from Carica papaya. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLUTAMINE CYCLOTRANSFERASE, ... | Authors: | Guevara, T, Mallorqui-Fernandez, N, Garcia-Castellanos, R, Petersen, G.E, Lauritzen, C, Pedersen, J, Arnau, J, Gomis-Ruth, F.X, Sola, M. | Deposit date: | 2006-06-27 | Release date: | 2006-07-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Papaya Glutamine Cyclotransferase Shows a Singular Five-Fold Beta-Propeller Architecture that Suggests a Novel Reaction Mechanism. Biol.Chem., 387, 2006
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2IYN
| The co-factor-induced pre-active conformation in PhoB | Descriptor: | MAGNESIUM ION, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | Authors: | Sola, M, Drew, D.L, Blanco, A.G, Gomis-Ruth, F.X, Coll, M. | Deposit date: | 2006-07-19 | Release date: | 2006-08-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The Cofactor-Induced Pre-Active Conformation in Phob. Acta Crystallogr.,Sect.D, 62, 2006
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