2IWB
MecR1 unbound extracellular antibiotic-sensor domain.
Summary for 2IWB
Entry DOI | 10.2210/pdb2iwb/pdb |
Related | 2IWC 2IWD |
Descriptor | METHICILLIN RESISTANCE MECR1 PROTEIN, TETRAPEPTIDE, NICKEL (II) ION, ... (5 entities in total) |
Functional Keywords | antibiotic resistance, bacterial antibiotic resistance, methicillin resistance, beta-lactamic antibiotics, mrsa, beta-lactamase, penicillin-binding protein |
Biological source | STAPHYLOCOCCUS AUREUS More |
Total number of polymer chains | 2 |
Total formula weight | 30108.92 |
Authors | Marrero, A.,Mallorqui-Fernandez, G.,Guevara, T.,Garcia-Castellanos, R.,Gomis-Ruth, F.X. (deposition date: 2006-06-27, release date: 2006-07-04, Last modification date: 2023-12-13) |
Primary citation | Marrero, A.,Mallorqui-Fernandez, G.,Guevara, T.,Garcia-Castellanos, R.,Gomis-Ruth, F.X. Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance. J.Mol.Biol., 361:506-, 2006 Cited by PubMed: 16846613DOI: 10.1016/J.JMB.2006.06.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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