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1IVY
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BU of 1ivy by Molmil
PHYSIOLOGICAL DIMER HPP PRECURSOR
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rudenko, G, Bonten, E, D'Azzo, A, Hol, W.G.J.
Deposit date:1996-06-12
Release date:1997-04-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism.
Structure, 3, 1995
1P9W
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BU of 1p9w by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
Descriptor: General secretion pathway protein E, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1P9R
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BU of 1p9r by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
Descriptor: CHLORIDE ION, General secretion pathway protein E, ZINC ION
Authors:Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1PZK
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BU of 1pzk by Molmil
Cholera Toxin B-Pentamer Complexed With N-Acyl Phenyl Galactoside 9h
Descriptor: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1PV2
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BU of 1pv2 by Molmil
Native Form 2 E.coli Chaperone Hsp31
Descriptor: Chaperone protein hchA
Authors:Quigley, P.M, Korotkov, K, Baneyx, F, Hol, W.G.J.
Deposit date:2003-06-26
Release date:2004-01-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A new native EcHsp31 structure suggests a key role of structural flexibility for chaperone function.
Protein Sci., 13, 2004
1PZI
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BU of 1pzi by Molmil
Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a
Descriptor: Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1PZJ
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BU of 1pzj by Molmil
Cholera Toxin B-Pentamer Complexed With Nitrophenyl Galactoside 5
Descriptor: Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-ALPHA-BENZAMIDE, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-BETA-BENZAMIDE
Authors:Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J.
Deposit date:2003-07-11
Release date:2004-03-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
1M66
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BU of 1m66 by Molmil
Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine
Descriptor: 2-BROMO-6-CHLORO-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
Authors:Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2002-07-12
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
1M67
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BU of 1m67 by Molmil
Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-hydroxy-purine
Descriptor: 2-BROMO-6-HYDROXY-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
Authors:Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2002-07-12
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002
1DPB
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BU of 1dpb by Molmil
CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
Descriptor: DIHYDROLIPOYL-TRANSACETYLASE
Authors:Hendle, J, Hol, W.G.J.
Deposit date:1995-02-03
Release date:1995-04-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1DPD
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BU of 1dpd by Molmil
CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
Descriptor: DIHYDROLIPOYL-TRANSACETYLASE
Authors:Hendle, J, Hol, W.G.J.
Deposit date:1995-02-03
Release date:1995-04-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1DPC
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BU of 1dpc by Molmil
CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
Descriptor: DIHYDROLIPOYL-TRANSACETYLASE
Authors:Hendle, J, Hol, W.G.J.
Deposit date:1995-02-03
Release date:1995-04-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1EEI
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BU of 1eei by Molmil
CHOLERA TOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYL-ALPHA-D-GALACTOSE
Descriptor: 3-nitrophenyl alpha-D-galactopyranoside, PROTEIN (CHOLERA TOXIN B)
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:2000-01-31
Release date:2000-02-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Acta Crystallogr.,Sect.D, 57, 2001
1CHQ
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BU of 1chq by Molmil
SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
1CHP
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BU of 1chp by Molmil
SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHLORIDE ION, CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
1ATH
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BU of 1ath by Molmil
THE INTACT AND CLEAVED HUMAN ANTITHROMBIN III COMPLEX AS A MODEL FOR SERPIN-PROTEINASE INTERACTIONS
Descriptor: ANTITHROMBIN III
Authors:Schreuder, H.A, Hol, W.G.J.
Deposit date:1993-12-14
Release date:1995-02-07
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions.
Nat.Struct.Biol., 1, 1994
1BTM
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BU of 1btm by Molmil
TRIOSEPHOSPHATE ISOMERASE (TIM) COMPLEXED WITH 2-PHOSPHOGLYCOLIC ACID
Descriptor: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Delboni, L.F, Mande, S.C, Hol, W.G.J.
Deposit date:1995-11-11
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of recombinant triosephosphate isomerase from Bacillus stearothermophilus. An analysis of potential thermostability factors in six isomerases with known three-dimensional structures points to the importance of hydrophobic interactions.
Protein Sci., 4, 1995
3TIM
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BU of 3tim by Molmil
THE CRYSTAL STRUCTURE OF THE "OPEN" AND THE "CLOSED" CONFORMATION OF THE FLEXIBLE LOOP OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
Descriptor: TRIOSEPHOSPHATE ISOMERASE
Authors:Wierenga, R.K.
Deposit date:1990-05-15
Release date:1991-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase.
Proteins, 10, 1991
5P2P
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BU of 5p2p by Molmil
X-RAY STRUCTURE OF PHOSPHOLIPASE A2 COMPLEXED WITH A SUBSTRATE-DERIVED INHIBITOR
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2, PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER
Authors:Dijkstra, B.W, Thunnissen, M.M.G.M, Kalk, K.H, Drenth, J.
Deposit date:1990-09-01
Release date:1991-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.
Nature, 347, 1990
6VYE
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BU of 6vye by Molmil
6-phosphogluconolactonase from Trypanosoma cruzi
Descriptor: 6-phosphogluconolactonase, GLYCEROL, PHOSPHATE ION
Authors:Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2020-02-26
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:6-phosphogluconolactonase from Trypanosoma cruzi
To be published
1MDA
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BU of 1mda by Molmil
CRYSTAL STRUCTURE OF AN ELECTRON-TRANSFER COMPLEX BETWEEN METHYLAMINE DEHYDROGENASE AND AMICYANIN
Descriptor: AMICYANIN, COPPER (II) ION, METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), ...
Authors:Chen, L, Durley, R, Mathews, F.S.
Deposit date:1992-03-02
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of an electron-transfer complex between methylamine dehydrogenase and amicyanin.
Biochemistry, 31, 1992
4PHC
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BU of 4phc by Molmil
Crystal Structure of a human cytosolic histidyl-tRNA synthetase, histidine-bound
Descriptor: GLYCEROL, HISTIDINE, Histidine--tRNA ligase, ...
Authors:Koh, C.Y, Wetzel, A.B, de van der Schueren, W.J, Hol, W.G.J.
Deposit date:2014-05-06
Release date:2014-08-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.844 Å)
Cite:Comparison of histidine recognition in human and trypanosomatid histidyl-tRNA synthetases.
Biochimie, 106, 2014
3C3W
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BU of 3c3w by Molmil
Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR
Descriptor: SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR
Authors:Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J.
Deposit date:2008-01-28
Release date:2008-04-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation
J.Mol.Biol., 378, 2008
2QV8
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BU of 2qv8 by Molmil
Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio cholerae
Descriptor: General secretion pathway protein H
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-08-07
Release date:2008-02-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the minor pseudopilin EpsH from the Type 2 secretion system of Vibrio cholerae.
J.Mol.Biol., 377, 2008
2RET
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BU of 2ret by Molmil
The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus
Descriptor: CHLORIDE ION, EpsJ, Pseudopilin EpsI, ...
Authors:Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J.
Deposit date:2007-09-27
Release date:2008-02-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus.
J.Mol.Biol., 375, 2008

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