4YCW
| Crystal structure of cladosporin in complex with plasmodium like human lysyl-tRNA synthetase mutant | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, Lysine--tRNA ligase, ... | Authors: | Fang, P, Wang, J, Guo, M. | Deposit date: | 2015-02-20 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor Chem.Biol., 22, 2015
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5YEG
| Crystal structure of CTCF ZFs4-8-Hs5-1a complex | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*TP*AP*AP*CP*CP*AP*GP*CP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*GP*CP*TP*GP*GP*TP*TP*AP*AP*AP*G)-3'), Transcriptional repressor CTCF, ... | Authors: | Yin, M, Wang, J, Wang, M, Li, X. | Deposit date: | 2017-09-17 | Release date: | 2017-11-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
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5YKS
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1S03
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1R8A
| Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes | Descriptor: | MANGANESE (II) ION, SODIUM ION, tRNA nucleotidyltransferase | Authors: | Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A. | Deposit date: | 2003-10-23 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes Mol.Cell, 12, 2003
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1R8B
| Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Xiong, Y, Li, F, Wang, J, Weiner, A.M, Steitz, T.A. | Deposit date: | 2003-10-23 | Release date: | 2003-12-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes Mol.Cell, 12, 2003
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4YCU
| Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, LYSINE, ... | Authors: | Fang, P, Wang, J, Guo, M. | Deposit date: | 2015-02-20 | Release date: | 2015-06-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor. Chem. Biol., 22, 2015
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5AX8
| Recombinant expression, purification and preliminary crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase | Descriptor: | Aspartate aminotransferase, mitochondrial | Authors: | Jiang, X, Wang, J, Chang, H, Zhou, Y. | Deposit date: | 2015-07-20 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase Biosci Trends, 10, 2016
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2O9Q
| The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K | Descriptor: | CALCIUM ION, Cationic trypsin, ORB2K, ... | Authors: | Li, J, Zhang, C, Xu, X, Wang, J, Gong, W, Lai, R. | Deposit date: | 2006-12-14 | Release date: | 2007-12-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | From protease inhibitor to antibiotics: single point mutation makes tremendous functional shift To be Published
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1V6P
| Crystal structure of Cobrotoxin | Descriptor: | CHLORIDE ION, COPPER (II) ION, Cobrotoxin, ... | Authors: | Lou, X, Tu, X, Wang, J, Teng, M, Niu, L, Liu, Q, Huang, Q, Hao, Q. | Deposit date: | 2003-12-03 | Release date: | 2004-12-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.87 Å) | Cite: | The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing J.Biol.Chem., 279, 2004
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5B6L
| Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | Descriptor: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | Authors: | Dong, W, Wang, J, Liu, L. | Deposit date: | 2016-05-30 | Release date: | 2016-09-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803 Febs Lett., 590, 2016
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5A1Z
| Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, ENVELOPE PROTEIN, ... | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Jr, J.E, Lok, S.M. | Deposit date: | 2015-05-06 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
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1TF7
| Crystal Structure of Circadian Clock Protein KaiC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, KaiC | Authors: | Pattanayek, R, Wang, J, Mori, T, Xu, Y, Johnson, C.H, Egli, M. | Deposit date: | 2004-05-26 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Visualizing a Circadian Clock Protein; Crystal Structure of KaiC and Functional Insights Mol.Cell, 15, 2004
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4IXP
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4MSR
| RNA 10mer duplex with six 2'-5'-linkages | Descriptor: | RNA 10mer duplex with six 2'-5'-linkages, STRONTIUM ION | Authors: | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | Deposit date: | 2013-09-18 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural insights into the effects of 2'-5' linkages on the RNA duplex. Proc.Natl.Acad.Sci.USA, 111, 2014
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6ULW
| Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module | Descriptor: | Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION | Authors: | Alonzo, D.A, Wang, J, Chiche-Lapierre, C, Schmeing, T.M. | Deposit date: | 2019-10-08 | Release date: | 2020-02-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16, 2020
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6UIB
| Crystal structure of IL23 bound to peptide 23-652 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... | Authors: | Durbin, J.D, Wang, J, Afshar, S. | Deposit date: | 2019-09-30 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage. Plos One, 15, 2020
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7WKH
| the grass carp IFNa | Descriptor: | Interferon | Authors: | Zou, J, WANG, J, Wang, Z. | Deposit date: | 2022-01-09 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish. Front Immunol, 13, 2022
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8TJM
| Crystal structure of KPC-44 carbapenemase | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, beta-lactamase | Authors: | Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. | Deposit date: | 2023-07-23 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
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8TMT
| Crystal structure of KPC-44 carbapenemase in complex with vaborbactam | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, LITHIUM ION, ... | Authors: | Sun, Z, Palzkill, T, Hu, L, Neetu, N, Lin, H, Sankaran, B, Wang, J, Prasad, B. | Deposit date: | 2023-07-30 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
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8TN0
| Crystal structure of KPC-44 carbapenemase w/o cryoprotectant | Descriptor: | SULFATE ION, beta-lactamase | Authors: | Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. | Deposit date: | 2023-07-31 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
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8TMR
| Crystal structure of KPC-44 carbapenemase complexed with avibactam | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, PHOSPHATE ION, ... | Authors: | Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B. | Deposit date: | 2023-07-30 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
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6WAX
| C-terminal SH2 domain of p120RasGAP | Descriptor: | 1,2-ETHANEDIOL, Ras GTPase-activating protein 1, SULFATE ION | Authors: | Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J. | Deposit date: | 2020-03-26 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain. J.Biol.Chem., 295, 2020
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6WB8
| Cryo-EM structure of PKD2 C331S disease variant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | Authors: | Cao, E, Wang, J, Decaen, P.G. | Deposit date: | 2020-03-26 | Release date: | 2020-04-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WAY
| C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide | Descriptor: | Ras GTPase-activating protein 1, Rho GTPase-activating protein 35 | Authors: | Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J. | Deposit date: | 2020-03-26 | Release date: | 2020-06-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain. J.Biol.Chem., 295, 2020
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