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The ClassB RSC-Nucleosome Complex
Descriptor:	Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
Authors:	Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
Deposit date:	2019-09-06
Release date:	2019-11-13
Last modified:	2024-05-29
Method:	ELECTRON MICROSCOPY (7.55 Å)
Cite:	Structure of the RSC complex bound to the nucleosome. Science, 366, 2019

6LQ3

Crystal Structure of E447A Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C12CoA
Descriptor:	Acyl-CoA dehydrogenase, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:	Liu, X, Chen, X.B.
Deposit date:	2020-01-12
Release date:	2020-07-01
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc.Natl.Acad.Sci.USA, 117, 2020

6LQ7

Crystal Structure of E447A Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C17CoA
Descriptor:	Acyl-CoA dehydrogenase, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:	Liu, X, Chen, X.B.
Deposit date:	2020-01-13
Release date:	2020-07-01
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc.Natl.Acad.Sci.USA, 117, 2020

6LQ8

Crystal Structure of E447A Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C22CoA
Descriptor:	Acyl-CoA dehydrogenase, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:	Liu, X, Chen, X.B.
Deposit date:	2020-01-13
Release date:	2020-11-25
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc.Natl.Acad.Sci.USA, 117, 2020

6LPY

Crystal Structure of E447A Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C4CoA
Descriptor:	Acyl-CoA dehydrogenase, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:	Liu, X, Chen, X.B.
Deposit date:	2020-01-12
Release date:	2020-07-01
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc.Natl.Acad.Sci.USA, 117, 2020

6LQ5

Crystal Structure of E447A Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C16CoA
Descriptor:	Acyl-CoA dehydrogenase, COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:	Liu, X, Chen, X.B.
Deposit date:	2020-01-13
Release date:	2020-07-01
Last modified:	2024-03-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proc.Natl.Acad.Sci.USA, 117, 2020

3N2Y

Crystal structure of tyrosyl-tRNA synthetase complexed with p-(2-tetrazolyl)-phenylalanine
Descriptor:	4-(2H-tetrazol-2-yl)-L-phenylalanine, Tyrosyl-tRNA synthetase
Authors:	Wu, M, Li, J, Zang, J.
Deposit date:	2010-05-19
Release date:	2010-11-03
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.49 Å)
Cite:	A biosynthetic route to photoclick chemistry on proteins J.Am.Chem.Soc., 132, 2010

7PN6

Evolved unspecific peroxygenase with A77L mutation in complex with myristic acid
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PN7

Evolved unspecific peroxygenase with A77L mutation in complex with palmitoleic acid
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PN5

Evolved unspecific peroxygenase with A77L mutation in complex with hexane
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.82 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PNA

Evolved unspecific peroxygenase with A77L mutation in complex with 12-methoxylauric acid
Descriptor:	12-methoxylauric acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PN8

Evolved unspecific peroxygenase with A77L mutation in complex with tetradecane
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PN4

Evolved unspecific peroxygenase with A77L mutation in complex with naphthalene
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

7PN9

Evolved unspecific peroxygenase with A77L mutation in complex with lauric acid
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Aromatic peroxygenase, CHLORIDE ION, ...
Authors:	Fernandez-Garcia, A, Sanz-Aparicio, J.
Deposit date:	2021-09-06
Release date:	2023-01-25
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids. Angew.Chem.Int.Ed.Engl., 62, 2023

6M4S

Crystal Structure Analysis of the cytochrome P450 CYP-Sb21
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Cytochrome P450 hydroxylase sb21, ...
Authors:	Li, F.W, Li, S.Y.
Deposit date:	2020-03-09
Release date:	2021-02-03
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana . Synth Syst Biotechnol, 5, 2020

6PI7

Crystal structure of the TDRD2 extended Tudor domain in complex with an antibody fragment and the PIWIL1 peptide
Descriptor:	Fab antigen-binding fragment, Piwi-like protein 1, Tudor and KH domain-containing protein, ...
Authors:	Liu, K, Min, J.R, Structural Genomics Consortium (SGC)
Deposit date:	2019-06-26
Release date:	2019-07-24
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1. Methods, 175, 2020

7QWM

TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-25
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (2.76 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QVF

TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-21
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (3.64 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

7QVC

TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-21
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (2.64 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

6M19

Template lasso peptide C24 mutant W14F
Descriptor:	lasso peptide
Authors:	Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M.
Deposit date:	2020-02-25
Release date:	2021-03-03
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021

5KHU

Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution
Descriptor:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:	Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B.
Deposit date:	2016-06-15
Release date:	2016-09-07
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (4.8 Å)
Cite:	Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016

5KHR

Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C)
Descriptor:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:	VanderLinden, R, Yamaguchi, M, Dube, P, Haselbach, D, Stark, H, Schulman, B.A.
Deposit date:	2016-06-15
Release date:	2016-08-24
Last modified:	2024-03-06
Method:	ELECTRON MICROSCOPY (6.1 Å)
Cite:	Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol.Cell, 63, 2016

5KJ0

CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH DB-1-264-2
Descriptor:	1,2-ETHANEDIOL, 4-[[(7~{R})-8-cyclopentyl-7-ethyl-5-methyl-6-oxidanylidene-7~{H}-pteridin-2-yl]-methyl-amino]-3-methoxy-~{N}-(1-methylpiperidin-4-yl)benzamide, Bromodomain-containing protein 4
Authors:	Zhu, J.-Y, Ember, S.W, Schonbrunn, E.
Deposit date:	2016-06-17
Release date:	2017-08-09
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET. ChemMedChem, 11, 2016

6QK9

A dimeric ubiquitin formed by a single amino acid substitution
Descriptor:	Polyubiquitin-B
Authors:	Gabrielsen, M, Kowalczyk, D, Buetow, L, Huang, D.T.
Deposit date:	2019-01-28
Release date:	2019-07-24
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.231 Å)
Cite:	Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation. Structure, 27, 2019

7QWL

TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor:	Transmembrane protein 106B
Authors:	Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:	2022-01-25
Release date:	2022-03-09
Last modified:	2022-05-25
Method:	ELECTRON MICROSCOPY (3.47 Å)
Cite:	Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature, 605, 2022

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Total results:	1007
Displayed results:	25
Sorted by:	Hit score (from highest)