6Y23
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5LF2
| Crystal structure of laminin beta2 LE5-LF-LE6 | Descriptor: | CALCIUM ION, CHLORIDE ION, Laminin subunit beta-2 | Authors: | Pulido, D, Hohenester, E. | Deposit date: | 2016-06-30 | Release date: | 2016-07-27 | Last modified: | 2017-03-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains. Matrix Biol., 57-58, 2017
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5AO6
| Endo180 D1-4, trigonal form | Descriptor: | C-TYPE MANNOSE RECEPTOR 2 | Authors: | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | Deposit date: | 2015-09-09 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.36 Å) | Cite: | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4. Structure, 23, 2015
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5AO5
| Endo180 D1-4, monoclinic form | Descriptor: | C-TYPE MANNOSE RECEPTOR 2, SODIUM ION, SULFATE ION | Authors: | Paracuellos, P, Briggs, D.C, Carafoli, F, Loncar, T, Hohenester, E. | Deposit date: | 2015-09-09 | Release date: | 2015-10-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Insights Into Collagen Uptake by C-Type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4. Structure, 23, 2015
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2C5D
| Structure of a minimal Gas6-Axl complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2005-10-26 | Release date: | 2005-12-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis for Gas6-Axl Signalling. Embo J., 25, 2006
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2Y38
| LAMININ ALPHA5 CHAIN N-TERMINAL FRAGMENT | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LAMININ SUBUNIT ALPHA-5, ... | Authors: | Hussain, S.A, Carafoli, F, Hohenester, E. | Deposit date: | 2010-12-19 | Release date: | 2011-02-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Determinants of Laminin Polymerisation Revealed by the Crystal Structure of the Alpha5 Chain Amino-Terminal Region Embo Rep., 12, 2011
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1GL4
| Nidogen-1 G2/Perlecan IG3 Complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, NIDOGEN-1, ... | Authors: | Kvansakul, M, Hopf, M, Ries, A, Timpl, R, Hohenester, E. | Deposit date: | 2001-08-23 | Release date: | 2001-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan Embo J., 20, 2001
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1GR3
| Structure of the human collagen X NC1 trimer | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ... | Authors: | Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E. | Deposit date: | 2001-12-12 | Release date: | 2002-02-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer. Structure, 10, 2002
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2DKB
| DIALKYLGLYCINE DECARBOXYLASE STRUCTURE: BIFUNCTIONAL ACTIVE SITE AND ALKALI METAL BINDING SITES | Descriptor: | 2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Toney, M.D, Hohenester, E, Jansonius, J.N. | Deposit date: | 1994-07-12 | Release date: | 1994-10-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dialkylglycine decarboxylase structure: bifunctional active site and alkali metal sites. Science, 261, 1993
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4AUO
| Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide | Descriptor: | CALCIUM ION, INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, ... | Authors: | Manka, S.W, Carafoli, F, Visse, R, Bihan, D, Raynal, N, Farndale, R.W, Murphy, G, Enghild, J.J, Hohenester, E, Nagase, H. | Deposit date: | 2012-05-18 | Release date: | 2012-07-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1 Proc.Natl.Acad.Sci.USA, 109, 2012
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4BJ3
| Integrin alpha2 I domain E318W-collagen complex | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GFOGER PEPTIDE, ... | Authors: | Carafoli, F, Hamaia, S.W, Bihan, D, Hohenester, E, Farndale, R.W. | Deposit date: | 2013-04-16 | Release date: | 2013-11-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.042 Å) | Cite: | An Activating Mutation Reveals a Second Binding Mode of the Integrin Alpha2 I Domain to the Gfoger Motif in Collagens. Plos One, 8, 2013
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5IK7
| Laminin A2LG45 I-form, Apo. | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | Deposit date: | 2016-03-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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5IK4
| Laminin A2LG45 C-form, Apo. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | Deposit date: | 2016-03-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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5IK5
| Laminin A2LG45 C-form, G6/7 bound. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ... | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | Deposit date: | 2016-03-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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5IK8
| Laminin A2LG45 I-form, G6/7 bound. | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ... | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | Deposit date: | 2016-03-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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5MX1
| Crystal structure of human chondroadherin | Descriptor: | CHLORIDE ION, Chondroadherin, NICKEL (II) ION, ... | Authors: | Paracuellos, P, Hohenester, E. | Deposit date: | 2017-01-20 | Release date: | 2017-03-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biol., 63, 2017
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5MX0
| Crystal structure of human fibromodulin | Descriptor: | CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ... | Authors: | Paracuellos, P, Hohenester, E. | Deposit date: | 2017-01-20 | Release date: | 2017-03-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biol., 63, 2017
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5MC9
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1H4U
| Domain G2 of mouse nidogen-1 | Descriptor: | NIDOGEN-1 | Authors: | Hopf, M, Gohring, W, Ries, A, Timpl, R, Hohenester, E. | Deposit date: | 2001-05-14 | Release date: | 2001-06-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure and Mutational Analysis of a Perlecan-Binding Fragment of Nidogen-1 Nat.Struct.Biol., 8, 2001
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1H30
| C-terminal LG domain pair of human Gas6 | Descriptor: | CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION | Authors: | Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2002-08-21 | Release date: | 2003-01-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains J.Biol.Chem., 277, 2002
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2WUH
| Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide | Descriptor: | COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2 | Authors: | Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E. | Deposit date: | 2009-10-05 | Release date: | 2009-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2 Structure, 17, 2009
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4AQS
| Laminin beta1 LN-LE1-4 structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LAMININ SUBUNIT BETA-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Carafoli, F, Hussain, S, Hohenester, E. | Deposit date: | 2012-04-19 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.109 Å) | Cite: | Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin Beta1 and Gamma1 Chains. Plos One, 7, 2012
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4AG4
| Crystal structure of a DDR1-Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1, ... | Authors: | Carafoli, F, Mayer, M.C, Shiraishi, K, Pecheva, M.A, Chan, L.Y, Nan, R, Leitinger, B, Hohenester, E. | Deposit date: | 2012-01-24 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling. Structure, 20, 2012
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4AQT
| Laminin gamma1 LN-LE1-2 structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LAMININ SUBUNIT GAMMA-1, ... | Authors: | Carafoli, F, Hussain, S, Hohenester, E. | Deposit date: | 2012-04-19 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structures of the Network-Forming Short-Arm Tips of the Laminin Beta1 and Gamma1 Chains. Plos One, 7, 2012
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1O91
| Crystal Structure of a Collagen VIII NC1 Domain Trimer | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, COLLAGEN ALPHA 1(VIII) CHAIN, SULFATE ION | Authors: | Kvansakul, M, Bogin, O, Hohenester, E, Yayon, A. | Deposit date: | 2002-12-10 | Release date: | 2003-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Collagen Alpha1(Viii) Nc1 Trimer. Matrix Biol., 22, 2003
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