4R1T
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![BU of 4r1t by Molmil](/molmil-images/mine/4r1t) | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | Descriptor: | cinnamoyl CoA reductase, molecular iodine | Authors: | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | Deposit date: | 2014-08-07 | Release date: | 2014-10-01 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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4DOO
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![BU of 4doo by Molmil](/molmil-images/mine/4doo) | Crystal structure of Arabidopsis thaliana fatty-acid binding protein At3g63170 (AtFAP1) | Descriptor: | Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION | Authors: | Noel, J.P, Pojer, F, Louie, G.V, Bowman, M.E. | Deposit date: | 2012-02-09 | Release date: | 2012-05-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis. Nature, 485, 2012
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4DOK
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![BU of 4dok by Molmil](/molmil-images/mine/4dok) | |
4R1U
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![BU of 4r1u by Molmil](/molmil-images/mine/4r1u) | Crystal structure of Medicago truncatula cinnamoyl-CoA reductase | Descriptor: | ACETATE ION, Cinnamoyl CoA reductase | Authors: | Noel, J.P, Bomati, E.K, Louie, G.V, Bowman, M.E. | Deposit date: | 2014-08-07 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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4DOL
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![BU of 4dol by Molmil](/molmil-images/mine/4dol) | |
4R1S
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![BU of 4r1s by Molmil](/molmil-images/mine/4r1s) | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, cinnamoyl CoA reductase | Authors: | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | Deposit date: | 2014-08-07 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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1OSH
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![BU of 1osh by Molmil](/molmil-images/mine/1osh) | A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR | Descriptor: | Bile acid receptor, METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE | Authors: | Downes, M, Verdecia, M.A, Roecker, A.J, Hughes, R, Hogenesch, J.B, Kast-Woelbern, H.R, Bowman, M.E, Ferrer, J.-L, Anisfeld, A.M, Edwards, P.A, Rosenfeld, J.M, Alvarez, J.G.A, Noel, J.P, Nicolaou, K.C, Evans, R.M. | Deposit date: | 2003-03-19 | Release date: | 2003-09-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR Mol.Cell, 11, 2003
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1ND7
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![BU of 1nd7 by Molmil](/molmil-images/mine/1nd7) | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase | Descriptor: | WW domain-containing protein 1 | Authors: | Verdecia, M.A, Joaziero, C.A.P, Wells, N.J, Ferrer, J.-L, Bowman, M.E, Hunter, T, Noel, J.P. | Deposit date: | 2002-12-08 | Release date: | 2003-09-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase Mol.Cell, 11, 2003
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1QLV
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![BU of 1qlv by Molmil](/molmil-images/mine/1qlv) | |
1D6I
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![BU of 1d6i by Molmil](/molmil-images/mine/1d6i) | CHALCONE SYNTHASE (H303Q MUTANT) | Descriptor: | CHALCONE SYNTHASE, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
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1D6F
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![BU of 1d6f by Molmil](/molmil-images/mine/1d6f) | CHALCONE SYNTHASE C164A MUTANT | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHALCONE SYNTHASE, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
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1D6H
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![BU of 1d6h by Molmil](/molmil-images/mine/1d6h) | CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) | Descriptor: | CHALCONE SYNTHASE, COENZYME A, SULFATE ION | Authors: | Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. | Deposit date: | 1999-10-13 | Release date: | 2000-02-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
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1INI
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![BU of 1ini by Molmil](/molmil-images/mine/1ini) | CRYSTAL STRUCTURE OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHETASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS, COMPLEXED WITH CDP-ME AND MG2+ | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHETASE, MAGNESIUM ION | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, A, Cane, D.E, Noel, J.P. | Deposit date: | 2001-05-14 | Release date: | 2001-11-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
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1INJ
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![BU of 1inj by Molmil](/molmil-images/mine/1inj) | CRYSTAL STRUCTURE OF THE APO FORM OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHETASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHETASE, CALCIUM ION | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, A, Cane, D.E, Noel, J.P. | Deposit date: | 2001-05-14 | Release date: | 2001-07-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
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1I88
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![BU of 1i88 by Molmil](/molmil-images/mine/1i88) | CHALCONE SYNTHASE (G256V) | Descriptor: | CHALCONE SYNTHASE 2, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
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1I8B
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![BU of 1i8b by Molmil](/molmil-images/mine/1i8b) | Chalcone synthase (G256F) | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
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1I86
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![BU of 1i86 by Molmil](/molmil-images/mine/1i86) | CHALCONE SYNTHASE, G256A MUTANT | Descriptor: | CHALCONE SYNTHASE 2, SULFATE ION | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
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1I52
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![BU of 1i52 by Molmil](/molmil-images/mine/1i52) | CRYSTAL STRUCTURE OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL (CDP-ME) SYNTHASE (YGBP) INVOLVED IN MEVALONATE INDEPENDENT ISOPRENOID BIOSYNTHESIS | Descriptor: | 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHASE, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Richard, S.B, Bowman, M.E, Kwiatkowski, W, Kang, I, Chow, C, Lillo, M, Cane, D.E, Noel, J.P. | Deposit date: | 2001-02-23 | Release date: | 2001-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis. Nat.Struct.Biol., 8, 2001
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1I89
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![BU of 1i89 by Molmil](/molmil-images/mine/1i89) | Chalcone synthase (G256L) | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-03-12 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure-guided programming of polyketide chain-length determination in chalcone synthase. Biochemistry, 40, 2001
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1JWX
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![BU of 1jwx by Molmil](/molmil-images/mine/1jwx) | Chalcone Synthase--F215S mutant | Descriptor: | CHALCONE SYNTHASE 2 | Authors: | Jez, J.M, Bowman, M.E, Noel, J.P. | Deposit date: | 2001-09-05 | Release date: | 2002-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity. Proc.Natl.Acad.Sci.USA, 99, 2002
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1U0U
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![BU of 1u0u by Molmil](/molmil-images/mine/1u0u) | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure | Descriptor: | Dihydropinosylvin synthase | Authors: | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | Deposit date: | 2004-07-14 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
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1U0W
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![BU of 1u0w by Molmil](/molmil-images/mine/1u0w) | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure | Descriptor: | Chalcone synthase 2, RESVERATROL | Authors: | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | Deposit date: | 2004-07-14 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
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1U0V
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![BU of 1u0v by Molmil](/molmil-images/mine/1u0v) | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization of Specificity of Type III Polyketide Synthases: 18xCHS structure | Descriptor: | Chalcone synthase 2 | Authors: | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | Deposit date: | 2004-07-14 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
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1U0M
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![BU of 1u0m by Molmil](/molmil-images/mine/1u0m) | Crystal Structure of 1,3,6,8-Tetrahydroxynaphthalene Synthase (THNS) from Streptomyces coelicolor A3(2): a Bacterial Type III Polyketide Synthase (PKS) Provides Insights into Enzymatic Control of Reactive Polyketide Intermediates | Descriptor: | GLYCEROL, POLYETHYLENE GLYCOL (N=34), putative polyketide synthase | Authors: | Austin, M.B, Izumikawa, M, Bowman, M.E, Udwary, D.W, Ferrer, J.L, Moore, B.S, Noel, J.P. | Deposit date: | 2004-07-13 | Release date: | 2004-09-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates J.Biol.Chem., 279, 2004
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5U3R
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![BU of 5u3r by Molmil](/molmil-images/mine/5u3r) | Human PPARdelta ligand-binding domain in complexed with specific agonist 2 | Descriptor: | 6-[2-({[4-(furan-2-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... | Authors: | Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. | Deposit date: | 2016-12-03 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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