1U0W
An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure
Summary for 1U0W
Entry DOI | 10.2210/pdb1u0w/pdb |
Related | 1BI5 1U0U 1U0V |
Descriptor | Chalcone synthase 2, RESVERATROL (3 entities in total) |
Functional Keywords | type iii polyketide synthase, pks, condensing enzyme, thiolase fold, alpha-beta-alpha-beta-alpha fold, aldol switch, catalytic triad, engineered resveratrol synthase, rs, sts, chs, chalcone synthase, stilbene synthase, transferase |
Biological source | Medicago sativa |
Total number of polymer chains | 4 |
Total formula weight | 172410.27 |
Authors | Austin, M.B.,Bowman, M.E.,Ferrer, J.-L.,Schroder, J.,Noel, J.P. (deposition date: 2004-07-14, release date: 2004-10-12, Last modification date: 2023-08-23) |
Primary citation | Austin, M.B.,Bowman, M.E.,Ferrer, J.-L.,Schroder, J.,Noel, J.P. An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11:1179-1194, 2004 Cited by PubMed: 15380179DOI: 10.1016/j.chembiol.2004.05.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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