9EUS

Mpro from SARS-CoV-2 with R298A mutation

Summary for 9EUS

Entry DOI	10.2210/pdb9eus/pdb
Descriptor	Replicase polyprotein 1a, GLYCEROL (3 entities in total)
Functional Keywords	sars-cov-2, main protease, oligomerization, viral protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	66942.29
Authors	Plewka, J.,Lis, K.,Czarna, A.,Pyrc, K.,Kantyka, T.,Chykunova, Y. (deposition date: 2024-03-28, release date: 2024-04-17, Last modification date: 2024-04-24)
Primary citation	Lis, K.,Plewka, J.,Menezes, F.,Bielecka, E.,Chykunova, Y.,Pustelny, K.,Niebling, S.,Garcia, A.S.,Garcia-Alai, M.,Popowicz, G.M.,Czarna, A.,Kantyka, T.,Pyrc, K. SARS-CoV-2 M pro oligomerization as a potential target for therapy. Int.J.Biol.Macromol., 267:131392-131392, 2024 Cited by PubMed: 38582483 DOI: 10.1016/j.ijbiomac.2024.131392 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation