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9EQK

WWP1 WW2-2,3-linker-WW3-WW4-HECT (WWP1-2L34H) with ordered WW2 domain

Summary for 9EQK
Entry DOI10.2210/pdb9eqk/pdb
DescriptorNEDD4-like E3 ubiquitin-protein ligase WWP1 (2 entities in total)
Functional Keywordsubiquitin, ligase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight130144.83
Authors
Dudey, A.P.,Hemmings, A.M. (deposition date: 2024-03-21, release date: 2024-05-15)
Primary citationDudey, A.P.,Rigby, J.M.,Hughes, G.R.,Stephenson, G.R.,Storr, T.E.,Chantry, A.,Hemmings, A.M.
Expanding the Inhibitor Space of the WWP1 and WWP2 HECT E3 Ligases
To Be Published,
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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PDB entries from 2024-06-12

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