8XBG

Human GPR34 -Gi complex bound to S3E-LysoPS, receptor focused

Summary for 8XBG

Entry DOI	10.2210/pdb8xbg/pdb
EMDB information	38217
Descriptor	Probable G-protein coupled receptor 34, (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[(~{Z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid (2 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	46254.39
Authors	Kawahara, R.,Shihoya, W.,Nureki, O. (deposition date: 2023-12-06, release date: 2024-05-15)
Primary citation	Izume, T.,Kawahara, R.,Uwamizu, A.,Chen, L.,Yaginuma, S.,Omi, J.,Kawana, H.,Hou, F.,Sano, F.K.,Tanaka, T.,Kobayashi, K.,Okamoto, H.H.,Kise, Y.,Ohwada, T.,Aoki, J.,Shihoya, W.,Nureki, O. Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15:902-902, 2024 Cited by PubMed: 38326347 DOI: 10.1038/s41467-024-45046-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.43 Å)

Structure validation