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8WTE

Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)

Summary for 8WTE
Entry DOI10.2210/pdb8wte/pdb
DescriptorT-cell receptor alpha chain, T-cell receptor beta chain, MHC class I antigen (Fragment), ... (6 entities in total)
Functional Keywordst cell receptor, kras-g12v, hla-a*11:01, immune system
Biological sourceMus musculus (house mouse)
More
Total number of polymer chains10
Total formula weight187611.10
Authors
Zhang, M.Y.,Luo, L.J.,Xu, W.,Guan, F.H.,Wang, X.Y.,Zhu, P.,Zhang, J.H.,Zhou, X.Y.,Wang, F.,Ye, S. (deposition date: 2023-10-18, release date: 2024-05-01, Last modification date: 2024-05-15)
Primary citationZhang, M.,Xu, W.,Luo, L.,Guan, F.,Wang, X.,Zhu, P.,Zhang, J.,Zhou, X.,Wang, F.,Ye, S.
Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen.
Commun Biol, 7:512-512, 2024
Cited by
PubMed: 38684865
DOI: 10.1038/s42003-024-06209-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.17 Å)
Structure validation

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