8WDX

Crystal structure of human FABP4 complexed with C3

Summary for 8WDX

Entry DOI	10.2210/pdb8wdx/pdb
Descriptor	Fatty acid-binding protein, adipocyte, 2-[(3-chloranyl-2-phenyl-phenyl)amino]-6-methyl-benzoic acid, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	lipid binding protein-inhibitor complex, lipid binding protein/inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	17311.14
Authors	Xie, H.,Chen, G.F.,Xu, Y.C. (deposition date: 2023-09-16, release date: 2023-12-27)
Primary citation	Chen, G.,Xie, H.,You, M.,Liu, J.,Shao, Q.,Li, M.,Su, H.,Xu, Y. Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3. Eur.J.Med.Chem., 264:115984-115984, 2023 Cited by PubMed: 38043490 DOI: 10.1016/j.ejmech.2023.115984 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation