8WD8

Cryo-EM structure of TtdAgo-guide DNA-target DNA complex

Summary for 8WD8

• Entry DOI: 10.2210/pdb8wd8/pdb
• EMDB information: 37457
• Descriptor: Argonaute family protein, Target DNA, Guide DNA, ... (5 entities in total)
• Functional Keywords: dna binding protein-dna complex, dna binding protein/dna
• Biological source: Thermus thermophilus; More
• Total number of polymer chains: 6
• Total formula weight: 195389.18

Authors

Zhuang, L. (deposition date: 2023-09-14, release date: 2024-01-31, Last modification date: 2024-02-28)

• Primary citation: Wang, L.,Chen, W.,Zhang, C.,Xie, X.,Huang, F.,Chen, M.,Mao, W.,Yu, N.,Wei, Q.,Ma, L.,Li, Z.; Molecular mechanism for target recognition, dimerization, and activation of Pyrococcus furiosus Argonaute.; Mol.Cell, 84:675-686.e4, 2024; PubMed: 38295801; DOI: 10.1016/j.molcel.2024.01.004

Experimental method

ELECTRON MICROSCOPY (2.9 Å)