8W48
Neutron and X-ray joint structure of WT-TTR in complex with piceatannol
Summary for 8W48
Entry DOI | 10.2210/pdb8w48/pdb |
Descriptor | Transthyretin, PICEATANNOL (3 entities in total) |
Functional Keywords | amyloidogenesis, inhibitor, neutron, thyroid hormone, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 35109.52 |
Authors | Yokoyama, T.,Kusaka, K.,Fujiwara, S. (deposition date: 2023-08-23, release date: 2023-11-22, Last modification date: 2023-12-06) |
Primary citation | Yokoyama, T.,Kusaka, K.,Mizuguchi, M.,Nabeshima, Y.,Fujiwara, S. Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66:15511-15523, 2023 Cited by PubMed: 37910439DOI: 10.1021/acs.jmedchem.3c01698 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (1.9 Å) X-RAY DIFFRACTION (1.19 Å) |
Structure validation
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