8VG7
Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT)
Summary for 8VG7
| Entry DOI | 10.2210/pdb8vg7/pdb |
| Descriptor | D-dopachrome decarboxylase (2 entities in total) |
| Functional Keywords | truncation, enzyme, cytokine, isomerase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 12563.50 |
| Authors | Parkins, A.,Pilien, A.,Wolff, A.,Thompson, M.C.,Pantouris, G. (deposition date: 2023-12-23, release date: 2024-05-01, Last modification date: 2024-05-22) |
| Primary citation | Parkins, A.,Pilien, A.V.R.,Wolff, A.M.,Argueta, C.,Vargas, J.,Sadeghi, S.,Franz, A.H.,Thompson, M.C.,Pantouris, G. The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67:7359-7372, 2024 Cited by PubMed: 38670943DOI: 10.1021/acs.jmedchem.4c00177 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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