8VG5

Crystal Structure of V113N Variant of D-Dopachrome Tautomerase (D-DT) Bound with 4CPPC

Summary for 8VG5

Entry DOI	10.2210/pdb8vg5/pdb
Descriptor	D-dopachrome decarboxylase, 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, CITRIC ACID, ... (4 entities in total)
Functional Keywords	truncation, enzyme, cytokine, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	50913.34
Authors	Parkins, A.,Pilien, A.,Thompson, M.C.,Pantouris, G. (deposition date: 2023-12-22, release date: 2024-05-01, Last modification date: 2024-05-22)
Primary citation	Parkins, A.,Pilien, A.V.R.,Wolff, A.M.,Argueta, C.,Vargas, J.,Sadeghi, S.,Franz, A.H.,Thompson, M.C.,Pantouris, G. The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67:7359-7372, 2024 Cited by PubMed: 38670943 DOI: 10.1021/acs.jmedchem.4c00177 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation