8V9Q

Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP.

Summary for 8V9Q

• Entry DOI: 10.2210/pdb8v9q/pdb
• Descriptor: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: gt-a fold catalytic domain, lectin domain, golgi membrane, mucin-type o-glycosyltransferase, transferase
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 5
• Total formula weight: 137158.67

Authors

Samara, N.L.,Collette, A.M. (deposition date: 2023-12-08, release date: 2024-03-13)

• Primary citation: Collette, A.M.,Hassan, S.A.,Schmidt, S.I.,Lara, A.J.,Yang, W.,Samara, N.L.; An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase.; Sci Adv, 10:eadj8829-eadj8829, 2024; PubMed: 38416819; DOI: 10.1126/sciadv.adj8829

Experimental method

X-RAY DIFFRACTION (2.29 Å)