8UYH

Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer

Summary for 8UYH

• Entry DOI: 10.2210/pdb8uyh/pdb
• EMDB information: 42804 42806 42807
• Descriptor: Serine/threonine-protein kinase Pink1, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION (3 entities in total)
• Functional Keywords: pink1, kinase, mitophagy, parkinson's disease, ubiquitin, phosphorylation, phospho-ubiquitin, transferase
• Biological source: Pediculus humanus corporis (human body louse)
• Total number of polymer chains: 2
• Total formula weight: 107192.51

Authors

Gan, Z.Y.,Kirk, N.S.,Leis, A.,Komander, D. (deposition date: 2023-11-13, release date: 2024-01-31)

• Primary citation: Gan, Z.Y.,Callegari, S.,Nguyen, T.N.,Kirk, N.S.,Leis, A.,Lazarou, M.,Dewson, G.,Komander, D.; Interaction of PINK1 with nucleotides and kinetin.; Sci Adv, 10:eadj7408-eadj7408, 2024; PubMed: 38241364; DOI: 10.1126/sciadv.adj7408

Experimental method

ELECTRON MICROSCOPY (2.84 Å)