8UQN

PLCb3-Gaq complex on membranes

Summary for 8UQN

• Entry DOI: 10.2210/pdb8uqn/pdb
• Related: 8UQO
• EMDB information: 42475 42476
• Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, GUANOSINE-5'-DIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: plcb3, gaq, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 181391.67

Authors

Falzone, M.E.,MacKinnon, R. (deposition date: 2023-10-24, release date: 2023-12-06)

• Primary citation: Falzone, M.E.,MacKinnon, R.; The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.; Proc.Natl.Acad.Sci.USA, 120:e2315011120-e2315011120, 2023; PubMed: 37991948; DOI: 10.1073/pnas.2315011120

Experimental method

ELECTRON MICROSCOPY (3.4 Å)