8UO8

Structure of synaptic vesicle protein 2B with padsevonil

This is a non-PDB format compatible entry.

Summary for 8UO8

• Entry DOI: 10.2210/pdb8uo8/pdb
• EMDB information: 42430
• Descriptor: Synaptic vesicle glycoprotein 2B, 2-acetamido-2-deoxy-beta-D-glucopyranose, (4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[(4R)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}pyrrolidin-2-one, ... (8 entities in total)
• Functional Keywords: synaptic vesicle, slc22, inhibitor, antiepileptic, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 81124.77

Authors

Martin, M.F.,Mittal, A.,Levin, E.,Adams, C.,Yang, M.,Ledecq, M.,Horyani, P.S.,Coleman, J.A. (deposition date: 2023-10-19, release date: 2024-05-22)

• Primary citation: Martin, M.F.,Coleman, J.A.; Structure of synaptic vesicle protein 2B with padsevonil; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)