8UIP

Cryo-EM Structure of Human Ninjurin1 curved oligomer

Summary for 8UIP

Entry DOI	10.2210/pdb8uip/pdb
EMDB information	42301
Descriptor	Ninjurin-1 (1 entity in total)
Functional Keywords	ninjurin1, ninj1, inflammation, inflammasome, pyroptosis, plasma membrane rupture, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	49070.99
Authors	David, L.,Wu, H. (deposition date: 2023-10-10, release date: 2024-05-01, Last modification date: 2024-05-08)
Primary citation	David, L.,Borges, J.P.,Hollingsworth, L.R.,Volchuk, A.,Jansen, I.,Garlick, E.,Steinberg, B.E.,Wu, H. NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks. Cell, 187:2224-2235.e16, 2024 Cited by PubMed: 38614101 DOI: 10.1016/j.cell.2024.03.008 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.3 Å)

Structure validation