8U8F
GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.
Summary for 8U8F
Entry DOI | 10.2210/pdb8u8f/pdb |
EMDB information | 42023 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | gpr3, orphan gpcr, gpcr, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 131533.92 |
Authors | Russell, I.C.,Belousoff, M.J.,Sexton, P. (deposition date: 2023-09-17, release date: 2024-03-06, Last modification date: 2024-03-13) |
Primary citation | Russell, I.C.,Zhang, X.,Bumbak, F.,McNeill, S.M.,Josephs, T.M.,Leeming, M.G.,Christopoulos, G.,Venugopal, H.,Flocco, M.M.,Sexton, P.M.,Wootten, D.,Belousoff, M.J. Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3. Biochemistry, 63:625-631, 2024 Cited by PubMed: 38376112DOI: 10.1021/acs.biochem.3c00647 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.49 Å) |
Structure validation
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