8U4P
Structure of AMD3100-bound CXCR4/Gi complex
Summary for 8U4P
Entry DOI | 10.2210/pdb8u4p/pdb |
EMDB information | 41888 41889 41890 41891 41892 41893 41894 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, chemokine receptor, plerixafor, amd3100, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 159939.56 |
Authors | |
Primary citation | Saotome, K.,McGoldrick, L.L.,Ho, J.,Ramlall, T.,Shah, S.,Moore, M.J.,Kim, J.H.,Leidich, R.,Olson, W.C.,Franklin, M.C. Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024 Cited by DOI: 10.1101/2024.02.09.579708PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.15 Å) |
Structure validation
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