8U4L
Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain
Summary for 8U4L
Entry DOI | 10.2210/pdb8u4l/pdb |
EMDB information | 41883 41884 41885 41886 |
Descriptor | Isoform JM-A CYT-1 of Receptor tyrosine-protein kinase erbB-4, Receptor tyrosine-protein kinase erbB-2, Isoform 6 of Pro-neuregulin-1, membrane-bound isoform, ... (9 entities in total) |
Functional Keywords | receptor tyrosine kinase, membrane protein, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 147541.77 |
Authors | Trenker, R.,Diwanji, D.,Bingham, T.,Verba, K.A.,Jura, N. (deposition date: 2023-09-10, release date: 2024-03-13) |
Primary citation | Trenker, R.,Diwanji, D.,Bingham, T.,Verba, K.A.,Jura, N. Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.31 Å) |
Structure validation
Download full validation report