8U26
Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786)
Summary for 8U26
Entry DOI | 10.2210/pdb8u26/pdb |
EMDB information | 24570 41840 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 141549.56 |
Authors | Chen, M.,Pintilie, G. (deposition date: 2023-09-05, release date: 2023-11-15, Last modification date: 2024-01-24) |
Primary citation | Chen, M.,Schmid, M.F.,Chiu, W. Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21:37-40, 2024 Cited by PubMed: 37973972DOI: 10.1038/s41592-023-02082-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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