8U1W

Structure of Norovirus (Hu/GII.4/Sydney/NSW0514/2012/AU) protease bound to inhibitor NV-004

Summary for 8U1W

• Entry DOI: 10.2210/pdb8u1w/pdb
• Related: 8U1V
• Related PRD ID: PRD_002347
• Descriptor: Peptidase C37, GLYCEROL, ACETATE ION, ... (5 entities in total)
• Functional Keywords: protease, 3-chymotrypsin-like protease, 3cl-pro, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
• Total number of polymer chains: 1
• Total formula weight: 20445.58

Authors

Eruera, A.R.,Campbell, A.C.,Krause, K.L. (deposition date: 2023-09-03, release date: 2023-12-20)

• Primary citation: Eruera, A.R.,McSweeney, A.M.,McKenzie-Goldsmith, G.M.,Opel-Reading, H.K.,Thomas, S.X.,Campbell, A.C.,Stubbing, L.,Siow, A.,Hubert, J.G.,Brimble, M.A.,Ward, V.K.,Krause, K.L.; Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease.; Viruses, 15:-, 2023; PubMed: 38005879; DOI: 10.3390/v15112202

Experimental method

X-RAY DIFFRACTION (1.84 Å)