8TH9

Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA

Summary for 8TH9

• Entry DOI: 10.2210/pdb8th9/pdb
• Descriptor: DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), ... (6 entities in total)
• Functional Keywords: neil2, dna glycosylase, dna lyase, lyase
• Biological source: Monodelphis domestica (gray short-tailed opossum); More
• Total number of polymer chains: 3
• Total formula weight: 41132.00

Authors

Eckenroth, B.E.,Doublie, S. (deposition date: 2023-07-14, release date: 2023-11-01, Last modification date: 2023-12-27)

• Primary citation: Eckenroth, B.E.,Bumgarner, J.D.,Matsumoto-Elliott, O.,David, S.S.,Doublie, S.; Structural and biochemical insights into NEIL2's preference for abasic sites.; Nucleic Acids Res., 51:12508-12521, 2023; PubMed: 37971311; DOI: 10.1093/nar/gkad1075

Experimental method

X-RAY DIFFRACTION (2.08 Å)