8TGP

Crystal structure of SIRT2 with FAM-PEG4-H4K16(myristoyl) peptide

Summary for 8TGP

• Entry DOI: 10.2210/pdb8tgp/pdb
• Descriptor: NAD-dependent protein deacetylase sirtuin-2, H4K16(myristoyl) peptide, ZINC ION, ... (5 entities in total)
• Functional Keywords: sirtuin sirtuin-2 sirt2, gene regulation, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 38225.53

Authors

Nicely, N.I.,Weiser, B.P. (deposition date: 2023-07-12, release date: 2024-01-24)

• Primary citation: Yang, J.,Nicely, N.I.,Weiser, B.P.; Effects of Dimerization on the Deacylase Activities of Human SIRT2.; Biochemistry, 62:3383-3395, 2023; PubMed: 37966275; DOI: 10.1021/acs.biochem.3c00381

Experimental method

X-RAY DIFFRACTION (1.76 Å)