8TGL

VMAT1 dimer with norepinephrine and reserpine

Summary for 8TGL

• Entry DOI: 10.2210/pdb8tgl/pdb
• EMDB information: 41240
• Descriptor: Chromaffin granule amine transporter, L-NOREPINEPHRINE, reserpine (3 entities in total)
• Functional Keywords: vmat, slc18, vascular monoamine transporter, monoamines, neurotransmitters, norepinephrine, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 101909.14

Authors

Ye, J.,Liu, B.,Li, W. (deposition date: 2023-07-12, release date: 2024-03-20, Last modification date: 2024-04-10)

• Primary citation: Ye, J.,Chen, H.,Wang, K.,Wang, Y.,Ammerman, A.,Awasthi, S.,Xu, J.,Liu, B.,Li, W.; Structural insights into vesicular monoamine storage and drug interactions.; Nature, 2024; PubMed: 38499039; DOI: 10.1038/s41586-024-07290-7

Experimental method

ELECTRON MICROSCOPY (3.4 Å)