8TFP
Fab from C10-S66K antibody in complex with carfentanil
Summary for 8TFP
| Entry DOI | 10.2210/pdb8tfp/pdb |
| Descriptor | Light chain of Fab from C10-S66K antibody, Heavy chain of Fab from C10-S66K antibody, Carfentanil, ... (4 entities in total) |
| Functional Keywords | antibody, fentanyl analogue, carfentanil, opioid., immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 94249.48 |
| Authors | Pholcharee, T.,Wilson, I.A. (deposition date: 2023-07-11, release date: 2023-08-16, Last modification date: 2023-09-20) |
| Primary citation | Eubanks, L.M.,Pholcharee, T.,Oyen, D.,Natori, Y.,Zhou, B.,Wilson, I.A.,Janda, K.D. An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. Acs Chem Neurosci, 14:2849-2856, 2023 Cited by PubMed: 37534714DOI: 10.1021/acschemneuro.3c00455 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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