8T9Z

Structural of M8C10 Fab in complex human metapneumovirus fusion protein

Summary for 8T9Z

Entry DOI	10.2210/pdb8t9z/pdb
Descriptor	Fusion glycoprotein F0, M8C10 Fab Heavy Chain, M8C10 Fab Light Chain, ... (4 entities in total)
Functional Keywords	neutralizing antibody, respiratory, metapneumovirus, fusion, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human metapneumovirus More
Total number of polymer chains	3
Total formula weight	100125.63
Authors	Su, H.P.,Eddins, M.J.,Shipman, J.M.,Kostas, J.,Reid, J.C. (deposition date: 2023-06-26, release date: 2023-11-22, Last modification date: 2023-12-27)
Primary citation	Xiao, X.,Wen, Z.,Chen, Q.,Shipman, J.M.,Kostas, J.,Reid, J.C.,Warren, C.,Tang, A.,Luo, B.,O'Donnell, G.,Fridman, A.,Chen, Z.,Vora, K.A.,Zhang, L.,Su, H.-P.,Eddins, M.J. Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface. J.Virol., 97:e0105223-e0105223, 2023 Cited by PubMed: 38032197 DOI: 10.1128/jvi.01052-23 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.995 Å)

Structure validation