8T84
Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes hexafluoroisopropanol
This is a non-PDB format compatible entry.
Summary for 8T84
| Entry DOI | 10.2210/pdb8t84/pdb |
| Descriptor | Racemic mixture of amyloid beta segment 35-MVGGVV-40, 1,1,1,3,3,3-hexafluoropropan-2-ol (3 entities in total) |
| Functional Keywords | rippled beta sheet, amyloid fibril, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 896.78 |
| Authors | Sawaya, M.R.,Raskatov, J.A.,Hazari, A. (deposition date: 2023-06-21, release date: 2023-11-29, Last modification date: 2023-12-13) |
| Primary citation | Hazari, A.,Sawaya, M.R.,Sajimon, M.,Vlahakis, N.,Rodriguez, J.,Eisenberg, D.,Raskatov, J.A. Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets. J.Am.Chem.Soc., 145:25917-25926, 2023 Cited by PubMed: 37972334DOI: 10.1021/jacs.3c11712 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.101 Å) |
Structure validation
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