8T7S

SpRYmer bound to NAC PAM DNA

This is a non-PDB format compatible entry.

Summary for 8T7S

• Entry DOI: 10.2210/pdb8t7s/pdb
• EMDB information: 41093
• Descriptor: CRISPR-associated endonuclease Cas9/Csn1, gRNA, TS, ... (6 entities in total)
• Functional Keywords: spry-cas9, crispr, cas9, immune system, r-loop, dimer
• Biological source: Streptococcus pyogenes; More
• Total number of polymer chains: 7
• Total formula weight: 432638.72

Authors

Hibshman, G.N.,Bravo, J.P.K.,Taylor, D.W. (deposition date: 2023-06-21, release date: 2024-05-01, Last modification date: 2024-05-15)

• Primary citation: Hibshman, G.N.,Bravo, J.P.K.,Hooper, M.M.,Dangerfield, T.L.,Zhang, H.,Finkelstein, I.J.,Johnson, K.A.,Taylor, D.W.; Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.; Nat Commun, 15:3663-3663, 2024; PubMed: 38688943; DOI: 10.1038/s41467-024-47830-3

Experimental method

ELECTRON MICROSCOPY (3.01 Å)