8T6V

Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)

Summary for 8T6V

Entry DOI	10.2210/pdb8t6v/pdb
EMDB information	41082
Descriptor	Band 3 anion transport protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ... (7 entities in total)
Functional Keywords	transmembrane, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	123139.72
Authors	Capper, M.J.,Zilberg, G.,Mathiharan, Y.K.,Yang, S.,Stone, A.C.,Wacker, D. (deposition date: 2023-06-18, release date: 2023-09-13, Last modification date: 2023-11-01)
Primary citation	Capper, M.J.,Yang, S.,Stone, A.C.,Vatansever, S.,Zilberg, G.,Mathiharan, Y.K.,Habib, R.,Hutchinson, K.,Zhao, Y.,Schlessinger, A.,Mezei, M.,Osman, R.,Zhang, B.,Wacker, D. Substrate binding and inhibition of the anion exchanger 1 transporter. Nat.Struct.Mol.Biol., 30:1495-1504, 2023 Cited by PubMed: 37679563 DOI: 10.1038/s41594-023-01085-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.95 Å)

Structure validation