8T4L

MD65 N332-GT5 SOSIP in complex with RM_N332_07 Fab and RM20A3 Fab

This is a non-PDB format compatible entry.

Summary for 8T4L

• Entry DOI: 10.2210/pdb8t4l/pdb
• EMDB information: 41035
• Descriptor: MD65 N332-GT5 SOSIP gp120, RM20A3 heavy chain Fv, RM20A3 light chain Fv, ... (9 entities in total)
• Functional Keywords: germline targeting, nhp, sosip, env, hiv, bg18, immunogen design, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 18
• Total formula weight: 384578.61

Authors

Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2023-06-09, release date: 2024-05-08, Last modification date: 2024-05-29)

• Primary citation: Steichen, J.M.,Phung, I.,Salcedo, E.,Ozorowski, G.,Willis, J.R.,Baboo, S.,Liguori, A.,Cottrell, C.A.,Torres, J.L.,Madden, P.J.,Ma, K.M.,Sutton, H.J.,Lee, J.H.,Kalyuzhniy, O.,Allen, J.D.,Rodriguez, O.L.,Adachi, Y.,Mullen, T.M.,Georgeson, E.,Kubitz, M.,Burns, A.,Barman, S.,Mopuri, R.,Metz, A.,Altheide, T.K.,Diedrich, J.K.,Saha, S.,Shields, K.,Schultze, S.E.,Smith, M.L.,Schiffner, T.,Burton, D.R.,Watson, C.T.,Bosinger, S.E.,Crispin, M.,Yates 3rd, J.R.,Paulson, J.C.,Ward, A.B.,Sok, D.,Crotty, S.,Schief, W.R.; Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates.; Science, 384:eadj8321-eadj8321, 2024; PubMed: 38753769; DOI: 10.1126/science.adj8321

Experimental method

ELECTRON MICROSCOPY (3.2 Å)