8T3L

TRPV1 in nanodisc bound with 2 LPA molecules in neighboring monomers

Summary for 8T3L

Entry DOI	10.2210/pdb8t3l/pdb
EMDB information	41005
Descriptor	Transient receptor potential cation channel subfamily V member 1, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ... (4 entities in total)
Functional Keywords	trpv1, lysophosphatidic acid, membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	294610.52
Authors	Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-06-07, release date: 2024-05-08, Last modification date: 2024-05-15)
Primary citation	Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38698206 DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation