8T2U

Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide

Summary for 8T2U

• Entry DOI: 10.2210/pdb8t2u/pdb
• EMDB information: 40988
• Descriptor: Integrin alpha-IIb, Integrin beta-3, Eptifibatide, ... (10 entities in total)
• Functional Keywords: complex, open headpiece, cell adhesion
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 198046.82

Authors

Adair, B.,Xiong, J.P.,Yeager, M.,Arnaout, M.A. (deposition date: 2023-06-06, release date: 2023-07-26)

• Primary citation: Adair, B.D.,Xiong, J.P.,Yeager, M.,Arnaout, M.A.; Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.; Nat Commun, 14:4168-4168, 2023; PubMed: 37443315; DOI: 10.1038/s41467-023-39763-0

Experimental method

ELECTRON MICROSCOPY (3.1 Å)