8T24

Crystal Structure of Porphyromonas gingivalis Sialidase (PG_0352)- Fructose bound in CBM

Summary for 8T24

Entry DOI	10.2210/pdb8t24/pdb
Related	8FEB 8T1Y 8T1Z
Descriptor	Sialidase, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
Functional Keywords	sialidase, neuraminidase, carbohydrate binding, virulence factor, hydrolase
Biological source	Porphyromonas gingivalis
Total number of polymer chains	1
Total formula weight	57826.65
Authors	Clark, N.D.,Malkowski, M.G. (deposition date: 2023-06-05, release date: 2023-10-04, Last modification date: 2023-10-11)
Primary citation	Clark, N.D.,Pham, C.,Kurniyati, K.,Sze, C.W.,Coleman, L.,Fu, Q.,Zhang, S.,Malkowski, M.G.,Li, C. Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors. Plos Pathog., 19:e1011674-e1011674, 2023 Cited by PubMed: 37747935 DOI: 10.1371/journal.ppat.1011674 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation