8SZL

Human liver-type glutaminase (Apo form)

Summary for 8SZL

Entry DOI	10.2210/pdb8szl/pdb
EMDB information	40920
Descriptor	Glutaminase liver isoform, mitochondrial (1 entity in total)
Functional Keywords	metabolic, cancer, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	265638.88
Authors	Feng, S.,Aplin, C.,Nguyen, T.-T.T.,Milano, S.K.,Cerione, R.A. (deposition date: 2023-05-30, release date: 2024-03-13)
Primary citation	Feng, S.,Aplin, C.,Nguyen, T.T.,Milano, S.K.,Cerione, R.A. Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15:1971-1971, 2024 Cited by PubMed: 38438397 DOI: 10.1038/s41467-024-46351-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.12 Å)

Structure validation